All-in-one solution for AAV downstream process: The PATfix system equipped with multiwavelength UV-detector, fluorescence, conductivity and pH sensor, and autosampler for high throughput applications, enables the impurity detection, total viral capsid recovery assessment, AAV capsid empty full separations and AAV8 purity quantification.
PATfix AAV Platform (excl. MALS) includes:
-Four distinct analytical methods to analyse:
- Impurities such as genomic DNA, proteins, and aggregates.
- Recoveries of Adeno-Associated Viruses (AAVs).
- The empty/full ratio of AAV8 capsids in purified samples.
- Separation of AAV capsids, assessing their heterogeneity and improving product quality regardless of AAV serotype.
-PATfix system
-PATfix software
-CIMac column for AAV platform