FectoVIR®-LV
FectoVIR®-AAV is a novel generation of synthetic transfection reagent specifically developed for industrial scale production of recombinant AAV (rAAV) in both suspension and adherent HEK-293 derivative cell systems
- Item No.:
- 101000189
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Lentiviral vectors are recognized to be the carrier of choice for allogenic or autologous cell therapies (such as CAR-T) because of its capacity to permanently integrate viral genome into host cell DNA. To produce those vectors, cell therapy producers generally use a transient transfection system that is scaled-up during process development phases. FectoVIR®-LV is the next generation of transfection reagent, free of animal component, designed to improve LV productivity in HEK-293 cell systems. FectoVIR®-LV is made for large scale manufacturing with reduction of the complexation volume and increased complex stability. The FectoVIR®-LV benefits allow to increase number of doses produced per batch to treat more patient, while decreasing LV manufacturing costs.
Take advantage of the complementary DOE service to fast-track optimization of lentivirus production with FectoVIR®-LV.
Key Benefits:
- Productivity: Reach the highest Lentiviral vectors titers in suspension systems.
- Cost-Effectiveness: Reduce your cost per batch with high titers and low DNA consumption.
- Scalability: Produce at large scale with low complexation volume and long complex stability.
- Time-Saving: Use DOE service to help you optimizing your process in a record time.
Application Notes
Datasheet
Poster
Technical Note
Applications
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ApplicationLentiviral vectors (LV) manufacturing using HEK-293 derivative cells cultivated in suspension
Biological Information
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Number of transfections100 mL of FectoVIR®-LV transfection reagent is sufficient to transfect on average 50 L of cell culture (using standard conditions)
Compliance Information
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Product Documentation
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Protocol
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Certificate of Analysis
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Non-hazardous product statement
- Certificate of origin
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Protocol
General Specifications
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Amount of ReagentFectoVIR®-LV 100 mL
Storage Conditions
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Storage Conditions5 °C ± 3 °C