Sartopure® GF Plus T-Style Maxicaps® 0.65 µm 20"

Sartopure^® GF Plus T-Style Maxicaps^®

Sartopure^® GF Plus T-Style Maxicaps^® are ready-to-use capsule depth filters for clarification and prefiltration in pharmaceutical and biopharmaceutical process streams. The T-style capsule configuration supports integration into single-use assemblies and flexible process layouts. The two-layer adsorptive glass-fiber fleece combines adsorptive and mechanical retention to reduce colloids, lipids, protein aggregates and particles before downstream filtration or purification steps.

Main Formats:

• Retention Ratings: Available with 0.65 µm and 1.2 µm retention ratings to support selection according to feed stream composition, particulate load and downstream process requirements.
• T-Style Maxicaps^® Format: Ready-to-use capsule format with T-style configuration for integration into disposable process assemblies.
• Single-Use Capsule Design: Enclosed filtration unit for applications where preassembled, disposable filtration components are preferred.
• Scalable Use: Suitable for process development, pilot-scale work and manufacturing applications, depending on selected size and process setup.
• Connector Options: Available with process-relevant connector configurations, such as Tri-Clamp or hose-barb options, depending on the selected article.

Applications:

• Cell Culture Harvest Clarification: Supports reduction of particles, colloids, lipids and protein aggregates in harvested cell culture fluids.
• Fermentation Broth Prefiltration: Suitable for clarification before downstream membrane filtration, chromatography or ultrafiltration steps.
• Media and Serum Filtration: Applicable for serum-free and serum-containing media, serum and process fluids with lipid or colloidal contaminants.
• Viscous Pharmaceutical Solutions: Can be used for prefiltration of viscous ophthalmic and large-volume parenteral solutions at appropriate process scale.
• Single-Use Bioprocessing: Designed for disposable processing lines where enclosed filtration units and flexible assembly layouts are required.
• Downstream Process Protection: Helps reduce particulate and colloidal load before membrane filters, chromatography columns and ultrafiltration systems.

Materials Used:

• Filter Medium: Two-layer glass-fiber fleece for combined adsorptive and mechanical retention.
• Support Material: Polypropylene support fleece.
• Capsule Housing: Polypropylene.
• Core and End Caps: Polypropylene.
• O-Rings: Silicone as standard, with EPDM or fluoroelastomer options depending on configuration and process requirements.
• Regulatory-Related Product Information: Non-pyrogenic according to USP Bacterial Endotoxins test and passes USP Plastic Class VI test, according to product documentation.

Advantages:

• T-Style Capsule Configuration: Supports flexible installation in single-use filtration assemblies and disposable process lines.
• Adsorptive Depth Filtration: The two-layer glass-fiber matrix supports reduction of colloids, lipids, protein aggregates and particles.
• Defined Retention Options: 0.65 µm and 1.2 µm ratings allow adaptation to different clarification and prefiltration needs.
• Ready-to-Use Handling: Enclosed capsule design can simplify setup compared with housing-based cartridge systems.
• Single-Use Integration: Suitable for workflows using disposable fluid paths and preassembled filtration units.
• Downstream Process Support: Helps reduce contaminant burden before final membrane filtration or purification operations.
• Process Flexibility: Different sizes and connector options support adaptation to development, pilot and manufacturing-scale setups.
• Sterilization Option: T-Style Maxicaps^® can be autoclaved within specified operating limits.

Together, these features make Sartopure^® GF Plus T-Style Maxicaps^® a practical capsule depth filtration option for clarification, prefiltration and downstream process protection in single-use biopharmaceutical and pharmaceutical workflows.