CMM HyperCel - 1 L
CMM HyperCel is a hydrophobic cation exchanger designed for the capture of antibodies, antibody fragments, and recombinant proteins. It allows the separation of proteins with similar pIs and hydrophobicity by modulation of pH and conductivity.
- Price (USD):
- $5,020.00
- Item No.:
- 20270-041
*Custom/bulk order quotes are provided within 72 hours of request.
Choose your CMM HyperCel
CMM HyperCel resin is composed of a rigid cellulose matrix that has flow properties compatible with the needs of manufacturing scale protein production.
The proprietary ligand, containing both a primary amine and a carboxyl group, confers cation exchange and hydrophobicity properties to the chromatography resin. The flexibility of the ligand enables the separation of proteins with a large variety of isoelectric points and hydrophobicity levels, and multiple conditions can be employed to separate targeted molecules from contaminants.
Features and Benefits
- Unique selectivity
- High capacity mixed-mode chromatography resin
- High recovery, low elution volume
- Easy CIP, NaOH stable
Applications
- Capture of MAbs, Fab fragments and recombinant proteins from challenging feedstocks
- Separation of proteins with similar isoelectric point and | or hydrophobicity at low or high conductivity
Applications
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ApplicationPreparative protein purification
Compliance Information
-
Quality StandardsCoA
Dimensions
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Bead Size50 - 80 µm
General Specifications
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Flow Rate100-600cm/h
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Resin FormatBulk resin
Materials of Construction
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Base MatrixRigid cellulose beads
Operating Conditions
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Maximum Operating Pressure< 3 barg (44psi)
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Operating Pressure< 3 barg (44psi)
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pH Stability1 to 14 (short term), 2 to 13 (long term)
Physicochemical Information
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LigandAminobenzoic acid
-
Reference Protein
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Bovine serum albumin (BSA)
- Human polyclonal IgG
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Bovine serum albumin (BSA)
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Typical Dynamic Binding Capacity 10% per mL> 50 mg/mL BSA at pH 4.5, 15 mS/cm; 60-100 mg/mL IgG at pH 4 to 5, 4-12 mS/cm
Product Information
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BrandCMM HyperCel
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Pack Size1
-
Pack Volume1 L
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Resin Delivery Condition1M NaCl with 20% EtOH
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Resin TypeMixed-mode cation exchanger
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What you receive1 bottle resin, instructions
Storage Conditions
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Storage Conditions20% EtOH/1M NaCl