Sartobind® S Capsule 1,200 mL with 8 mm bed height
Sartobind® S membrane adsorber units combine the advantages of convective media and ion exchange chromatography for rapid and easy contaminant removal or capture of virus and virus like particles.
- Item No.:
- 96IEXS42E3FSS
*Custom/bulk order quotes are provided within 72 hours of request.
Choose your Sartobind® S
Sartobind® S membrane adsorbers display a macro-porous structure with pore size of > 3 µm. Sulfonic acid ligands are bound covalently to the complete internal surface of the membrane, resulting in separation media of high binding capacity combined with exceptional high flow rates.
Applications:
The S membrane adsorber is successfully used in FDA-approved drug manufacture to remove host cell proteins at high flow rates. As a cation exchanger it displays not only aggregate removal capabilities but typically at least ten-fold higher binding capacity for viruses and virus-like-particles (VLP).
Benefits:
The Sartobind S adsorber speeds up the production process by high flow rate and opens new opportunities for the purification of therapeutic proteins and vaccines.
- High speed host cell protein removal up to 30 bed volumes/ min
- Aggregate removal
Easy to use:
- Plug and play devices from 0.08 ml to 5 l
- Can be used like a filter
- Flow rate up to 30 bed volumes/min
- Disposable or re-usable
Application Notes
Brochure
Datasheet
Flyer
User Manual
Applications
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Application
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Polishing
- Capture
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Polishing
Compliance Information
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Biological ReactivityAll materials of this filter element meet the requirements of the current USP Biological Reactivity tests <88> for plastics Class VI (Systemic Injection, Intracutaneous and Implantation tests).
Connections (Physical)
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Connector(s)Sanitary 1" – 1.5"
Dimensions
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Bed Height8 mm
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Dimensions WxDxH10 × 81 cm
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Membrane Area4.4 m²
Features
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ReusableYes
Materials of Construction
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Housing MaterialPolypropylene (PP)
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Materials of Construction
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Polypropylene
- Polyester
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Polypropylene
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Membrane MaterialStabilized reinforced cellulose
Operating Conditions
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Maximum Operating Pressure0.4 MPa
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Maximum Venting Pressure0.5 bar, 0.05 MPa, 7 psi
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Recommended Flow Rate6 L/min
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pH StabilitypH 3 – 14 (short term), pH 4 – 13 (long term)
Physicochemical Information
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Bed Volume1,200 mL
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LigandSulfonic acid
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Ligand Density2 – 5 µeq/cm²
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Pore Size3 – 5 µm
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Reference ProteinLysozyme
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Thermal StabilitySartobind capsules with ion exchange membranes can be autoclaved at 121 °C for 30 min. We recommend one autoclaving cycle only.
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Typical Dynamic Binding Capacity 10% per unit31 g
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Void Volume1.56 L
Product Information
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BrandSartobind® S
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Membrane Adsorber FormatCapsules
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Membrane TypeStrong cation exchanger
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Pack Size1
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TypeMembrane adsorber
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What you receive
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1 capsule
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1 operating instruction
- 1 certificate
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1 capsule