Sartobind® S Capsule 150 mL with 8 mm bed height

Sartobind® S membrane adsorber units combine the advantages of convective media and ion exchange chromatography for rapid and easy contaminant removal or capture of virus and virus like particles.

Bed Volume
Item No.: 
96IEXS42E9BFF
Availability: 

*Custom/bulk order quotes are provided within 72 hours of request.

Sartobind® S membrane adsorbers display a macro-porous structure with pore size of > 3 µm. Sulfonic acid ligands are bound covalently to the complete internal surface of the membrane, resulting in separation media of high binding capacity combined with exceptional high flow rates.

Applications:

The S membrane adsorber is successfully used in FDA-approved drug manufacture to remove host cell proteins at high flow rates. As a cation exchanger it displays not only aggregate removal capabilities but typically at least ten-fold higher binding capacity for viruses and virus-like-particles (VLP).

Benefits:

The Sartobind S adsorber speeds up the production process by high flow rate and opens new opportunities for the purification of therapeutic proteins and vaccines.

  • High speed host cell protein removal up to 30 bed volumes/ min
  • Aggregate removal

Easy to use:

  • Plug and play devices from 0.08 ml to 5 l
  • Can be used like a filter
  • Flow rate up to 30 bed volumes/min
  • Disposable or re-usable

Applications

  • Application
    • Polishing
    • Capture

Compliance Information

  • Biological Reactivity
    All materials of this filter element meet the requirements of the current USP Biological Reactivity tests <88> for plastics Class VI (Systemic Injection, Intracutaneous and Implantation tests).

Connections (Physical)

  • Connector(s)
    Sanitary 0.5" – 0.75"

Dimensions

  • Bed Height
    8 mm
  • Dimensions WxDxH
    7.7 × 19 cm
  • Membrane Area
    0.55 m²

Features

  • Reusable
    Yes

Materials of Construction

  • Housing Material
    Polypropylene (PP)
  • Materials of Construction
    • Polypropylene
    • Polyester
  • Membrane Material
    Stabilized reinforced cellulose

Operating Conditions

  • Maximum Operating Pressure
    0.4 MPa
  • Maximum Venting Pressure
    0.5 bar, 0.05 MPa, 7 psi
  • Recommended Flow Rate
    0.75 L/min
  • pH Stability
    pH 3 – 14 (short term), pH 4 – 13 (long term)

Physicochemical Information

  • Bed Volume
    150 mL
  • Ligand
    Sulfonic acid
  • Ligand Density
    2 – 5 µeq/cm²
  • Pore Size
    3 – 5 µm
  • Reference Protein
    Lysozyme
  • Thermal Stability
    Sartobind capsules with ion exchange membranes can be autoclaved at 121 °C for 30 min. We recommend one autoclaving cycle only.
  • Typical Dynamic Binding Capacity 10% per unit
    3.9 g
  • Void Volume
    200 mL

Product Information

  • Brand
    Sartobind® S
  • Membrane Adsorber Format
    Capsules
  • Membrane Type
    Strong cation exchanger
  • Pack Size
    1
  • Type
    Membrane adsorber
  • What you receive
    • 1 capsule
    • 1 operating instruction
    • 1 certificate
  • Adapter Sanitary 25 mm 1/2-3/4" to UNF 10-32, polyoxmethylene.

    Adapter Sanitary 25 mm 1/2-3/4" to UNF 10-32, polyoxmethylene.

  • MidiCaps® Holder
    Item no.
    5ZGLG-0007

    The Sartorius Stedim Biotech MidiCaps® holder has been specially designed to integrate MidiCaps® into biopharmaceutical processes.