CMM HyperCel is a hydrophobic cation exchanger designed for the capture of antibodies, antibody fragments, and recombinant proteins. It allows the separation of proteins with similar pIs and hydrophobicity by modulation of pH and conductivity.

Bed Volume
Price (USD):
$121.00
Item No.: 
PRCCMMHCEL1ML

*Custom/bulk order quotes are provided within 72 hours of request.

CMM HyperCel resin is composed of a rigid cellulose matrix that has flow properties compatible with the needs of manufacturing scale protein production.
The proprietary ligand, containing both a primary amine and a carboxyl group, confers cation exchange and hydrophobicity properties to the chromatography resin. The flexibility of the ligand enables the separation of proteins with a large variety of isoelectric points and hydrophobicity levels, and multiple conditions can be employed to separate targeted molecules from contaminants.

Features and Benefits

- Unique selectivity
- High capacity mixed-mode chromatography resin
- High recovery, low elution volume
- Easy CIP, NaOH stable

Applications

- Capture of MAbs, Fab fragments and recombinant proteins from challenging feedstocks
- Separation of proteins with similar isoelectric point and | or hydrophobicity at low or high conductivity

Applications

  • Application
    8799045452384  

Compliance Information

  • Quality Standards
    CoA  

Dimensions

  • Bead Size
    50 - 80 µm  
  • Bed Height
    50 mm  
  • Dimensions
    5 x 50 mm  

General Specifications

  • Flow Rate
    100-300cm/h  
  • Resin Format
    8799082218080  

Materials of Construction

  • Base Matrix
    8798948098656  
  • Materials of Construction
    Polypropylene  

Operating Conditions

  • Operating Pressure
    < 3 barg (44psi)  
  • pH Stability
    1 to 14 (short term), 2 to 13 (long term)  

Physicochemical Information

  • Bed Volume
    1 mL  
  • Ligand
    8805269275232  
  • Reference Protein
    • 8799080645216  
    • 8799080972896  
  • Typical Dynamic Binding Capacity 10% per mL
    > 50 mg/mL BSA at pH 4.5, 15 mS/cm; 60-100 mg/mL IgG at pH 4 to 5, 4-12 mS/cm  

Product Information

  • Brand
    8798957044320  
  • Pack Size
    1 column per pack  
  • Pack Volume
    1 mL  
  • Resin Delivery Condition
    8799082381920  
  • Resin Type
    8799082807904  
  • What you receive
    1 column, instructions  

Storage Conditions

  • Storage Conditions
    8799087067744