CIMmic® r-Protein A 0.1 mL Disk (Recombinant Protein A) (2 µm channels) - Pack of 3

CIMmic® r-Protein A disk provides an excellent solution for screening chromatographic conditions for purification of mouse and human immunoglobulin G (IgG) from different samples.

Article number: 
103.1004-2
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CIMmic® r-Protein A 0.1 mL Disk (Recombinant Protein A) (2 µm channels) - Pack of 3
CIMmic® r-Protein A 0.1 mL Disk (Recombinant Protein A) (2 µm channels) - Pack of 3

CIMmic® r-Protein A disk provides an excellent solution for screening chromatographic conditions for purification of mouse and human immunoglobulin G (IgG) from different samples.

Item No.:
103.1004-2

Overview

Specifications

CIMmic® r-Protein A disk are primarily intended for fast and efficient screening for capture and purification of immunoglobulin G (IgG) and other r-Protein A-binding antibodies from various samples.

r-Protein A features:

  • Primary binding to the hinge region of IgG-Fc of IgG, secondary binding to light chains of other antibody classes
  • Used for purification of mouse IgG, most subtypes of human IgG and many IgM monoclonal antibodies.

CIMmic® is a line of small monoliths that provide an easy, budget-friendly way to perform monolith chromatography. Operating with either an FPLC or a syringe provides an effortless way to start your process development.

The CIMmic line is the accessible entry point into CIM monolith chromatography for laboratories that need fast, flexible, and meaningful process development at small scale. Designed for early-stage method development and focused parameter screening, CIMmic helps scientists evaluate purification conditions without the need for complex automation, large sample volumes, or extensive chromatography infrastructure.

Benefits:

  • Very fast processes by convective mass transport – resolution independent of flow
  • High-capacity for large molecules due to fully accessible void volume in the channels
  • Laminar flow minimizes shear stress resulting in high yields
  • Ideal for early process development and feasibility testing
  • Operable by syringe or FPLC
  • Low sample and buffer consumption

Applications

  • Application
    • Screening
    • Purification
    • Antibody Purification

Compliance Information

  • GMP Compliance
    non-cGMP

Connections (Physical)

  • Connector(s)
    10-32 UNF coned port, 0.0625" OD tubing connection

Dimensions

  • Channel Size
    2 µm
  • Column Tube Length
    2.1 mm (monolith)
  • Diameter
    7.9 mm (monolith)

Features

  • Reusable
    Yes

General Specifications

  • Flow Rate
    0.2–3 mL/min; 0.5–7.5 cm/min; 2–30 CV/min

Materials of Construction

  • Materials of Construction
    Poly(glycidyl methacrylate -co- ethylene dimethacrylate)

Operating Conditions

  • Maximum Operating Pressure
    0.5 MPa, 5 bar, 70 psi
  • Recommended Operating Temperature
    4 °C (39 F) to 40 °C (104 °F)
  • pH Stability
    Working range 2–11

Physicochemical Information

  • Bed Volume
    0.1 mL
  • Ligand
    r-Protein A (affinity, recombinant protein A produced from E. Coli coupled to CDI-preactivated support)

Product Information

  • Brand
    CIMmic®

Volume

  • Volume
    0.1 mL