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CM Ceramic HyperD® F PRC Column - 1 mL

Tech Support Documents
CM Ceramic HyperD® F PRC Column - 1 mL
 

CM Ceramic HyperD® is a weak cation exchanger for biomolecule purification. Changes in conductivity and pH can optimize purification steps by utilizing the charge change on protein and ligand.

  • Pre-packed columns simplify resin screening and selection
  • Ideal for process step optimization
  • RoboColumn® format is especially suited for high throughput process development (HTPD)
Bed Volume
Item No.: 
PRC05X050CMCHDF
*Custom/bulk order quotes are provided within 72 hours of request.
CM Ceramic HyperD® F PRC Column - 1 mL
CM Ceramic HyperD® F PRC Column - 1 mL

CM Ceramic HyperD® is a weak cation exchanger for biomolecule purification. Changes in conductivity and pH can optimize purification steps by utilizing the charge change on protein and ligand.

  • Pre-packed columns simplify resin screening and selection
  • Ideal for process step optimization
  • RoboColumn® format is especially suited for high throughput process development (HTPD)
Item No.:
PRC05X050CMCHDF

Overview

Specifications

Choose your CM Ceramic HyperD® F

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CM Ceramic HyperD® F ion exchange chromatography resin is designed using proprietary gel-in-a-shell design that provides rapid mass transfer and effective binding. It relies on a high capacity hydrogel, polymerized within the gigapores of a rigid ceramic bead. This salt-tolerant resin reduces Ultrafiltration (UF) and Diafiltration (DF) requirements, enhancing process efficiency.

CM Ceramic HyperD® pre-packed columns are designed to simplify resin screening and selection, making them ideal for optimizing process steps. The RoboColumn® format is particularly suited for high throughput process development (HTPD), allowing for efficient and streamlined purification processes.

Features and Benefits

  • High dynamic binding capacity at high flow rates
  • Truly rigid, non-compressible resin
  • Salt tolerant CM Ceramic HyperD™ F resin reduces Ultrafiltration/Diafiltration (UF/DF) requirements

Applications

  • Recombinant proteins
  • Purification of enzymes, plasma proteins
  • Vaccines
  • Direct capture of monoclonal antibodies
  • IgM

Applications

  • Application
    Resin screening and process optimization

Compliance Information

  • Quality Standards
    • CoA
    • RSF (upon request)

Dimensions

  • Bead Size
    50 µm
  • Bed Height
    50 mm
  • Dimensions
    5 x 50 mm

General Specifications

  • Flow Rate
    300 to 600 cm/h (1 to 2 mL/min) with < 1.5 bar (22psi)
  • Resin Format
    Pre-packed column

Materials of Construction

  • Base Matrix
    Ceramic Beads
  • Materials of Construction
    Polypropylene

Operating Conditions

  • Operating Pressure
    < 3 barg (44psi)
  • pH Stability
    1 to 14 (short term), 2 to 12 (long term)

Physicochemical Information

  • Bed Volume
    1 mL
  • Ligand
    Carboxymethyl
  • Ligand Density
    250-400 µeq/mL
  • Reference Protein
    Human polyclonal IgG
  • Typical Dynamic Binding Capacity 10% per mL
    > 110 g/L

Product Information

  • Brand
    CM Ceramic HyperD®
  • Pack Size
    1 column per pack
  • Resin Delivery Condition
    20% EtOH/150 mM NaCl
  • Resin Type
    Weak cation exchanger
  • What you receive
    • 1x row of 8 columns
    • Instruction for use

Storage Conditions

  • Storage Conditions
    1M NaCl with 20% EtOH, 1.2 mM EDTA