Octet® Anti-Mouse Fc Capture (AMC) Biosensors

Octet® Anti-Mouse Fc Capture (AMC) Biosensors are designed for kinetic characterization of interactions between mouse Fc-containing proteins and target analytes. Octet® AMC Biosensors are offered in a tray format. Each tray contains 96 biosensors. Larger orders include discounts. The 5-tray pack represents a 10% per tray discount; 20-tray case represents a 20% per tray discount.

Key Features of Octet® Anti-Mouse Fc Capture (AMC) Biosensors

  • Capture-based immobilization of mouse Fc-containing proteins
  • Designed for use in buffer or complex media
  • Regenerable and cost-effective

Top Applications for Octet® Anti-Mouse Fc Capture (AMC) Biosensors

  • Complete kinetic analysis (ka, kd, KD) between mouse Fc-containing proteins and target analytes
  • Off-rate ranking of hybridoma and stable cell-line supernatants
  • Epitope binning/mapping from crude or purified samples

Note: This product is not returnable. If you have any issues with this product, please contact your Sartorius sales representative for assistance.

Price (USD):
$752.00
Item No.: 
18-5088
Availability: 
Piece
1

*Custom/bulk order quotes are provided within 24 hours of request.

The Octet® Anti-Mouse Fc Capture (AMC) Biosensors are designed for kinetic characterization of interactions between mouse Fc-containing proteins and target analytes. Immobilization of mouse Fc-containing proteins onto the biosensor surface is achieved through a factory immobilized anti-mouse Fc-specific antibody, whose high-affinity for the mouse Fc domain provides a stable baseline required for demanding kinetics applications. It is recommended to use the AMC biosensors with IgG1, IgG2a and IgG2b subtypes; IgG3 should be evaluated on a case-by-case basis.

Streamlined Workflow

The Octet® AMC Biosensors on the Octet® platform allow to streamline high-throughput kinetic screening by enabling immobilization of human Fc-containing proteins onto the biosensors directly from crude or purified matrices, without the need for labor intensive purification or biotinylation steps.

Flexible Applications

The AMC biosensors provide a flexible platform for evaluating the kinetics between mouse Fc-containing proteins and their analytes. The main applications for AMC biosensors include: Complete kinetic analysis (kon, koff and KD) between mouse Fc-containing proteins and target analytes Off-rate ranking of hybridoma and stable cell-line supernatants Epitope binning/mapping from either crude or purified samples Tracking product integrity by measuring kon, koff and KD during upstream fermentation, downstream harvest and purification, post-derivatization (pegylation) and formulation development.

Cost-Effective Regeneration

The Octet® AMC Biosensors can be regenerated up to 10 times via a standard low-pH protocol in as little as 2 minutes, thus providing a cost-effective solution for analyzing a large number of samples or generating replicate data for ligand-analyte pairs.

Applications

  • Application
    Kinetics  

Compliance Information

  • GMP Kits
    No  

Features

  • Device/Instrument Compatibility
    • Octet® R8  
    • Octet® R4  
    • Octet® R2  
    • Octet® RH96  
    • Octet® RED96e  
    • Octet® RH16  
    • Octet® N1  

Product Information

  • Brand
    Octet®BLI  
  • Pack Size
    1  
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  • Octet® 384 Well Tilted Bottom Plate

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  • Octet® Anti-Human Fc Capture (AHC) Biosensors

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    Key Features of Octet® Anti-Human Fc

    • Capture (AHC) Biosensors Capture-based immobilization of human Fc-containing proteins
    • Regenerable and cost-effective
    • Compatible with crude samples and complex media

    Top Applications for Octet® Anti-Human Fc Capture (AHC) Biosensors

    • Kinetic analysis of interactions between human Fc-containing proteins and target analytes
    • Rapid epitope mapping/binning

    Note: This product is not returnable. If you have any issues with this product, please contact your Sartorius sales representative for assistance.

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    Note: This product is not returnable. If you have any issues with this product, please contact your Sartorius sales representative for assistance.