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Q Ceramic HyperD® F PRC Column - 1 mL

Tech Support Documents
Q Ceramic HyperD® F PRC Column - 1 mL
 

Q Ceramic HyperD® is a strong anion exchanger that is suited for removal of anionic impurities (i.g., host cell protein and DNA). The 50 µm average particle size offers high resolution for polishing applications.

  • Pre-packed columns simplify resin screening and selection.
  • Ideal for process step optimization.
  • RoboColumn® format is especially suited for high throughput process development (HTPD).
Bed Volume
Item No.: 
PRC05X050QCHDF01
*Custom/bulk order quotes are provided within 72 hours of request.
Q Ceramic HyperD® F PRC Column - 1 mL
Q Ceramic HyperD® F PRC Column - 1 mL

Q Ceramic HyperD® is a strong anion exchanger that is suited for removal of anionic impurities (i.g., host cell protein and DNA). The 50 µm average particle size offers high resolution for polishing applications.

  • Pre-packed columns simplify resin screening and selection.
  • Ideal for process step optimization.
  • RoboColumn® format is especially suited for high throughput process development (HTPD).
Item No.:
PRC05X050QCHDF01

Overview

Specifications

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Q Ceramic HyperD® ion exchange chromatography resin is designed using proprietary "gel-in-a-shell" design that provides rapid mass transfer and effective binding. It relies on a high capacity hydrogel, polymerized within the gigapores of a rigid ceramic bead.

Q Ceramic HyperD® pre-packed columns are designed to simplify resin screening and selection, making them ideal for optimizing process steps. The RoboColumn® format is particularly suited for high throughput process development (HTPD), allowing for efficient and streamlined purification processes.

Features and Benefits

  • High dynamic binding capacity at high flow rates
  • Truly rigid, non-compressible resin

Applications

  • Recombinant proteins
  • Plasmid purification
  • Purification of enzymes, plasma proteins
  • Vaccines
  • IgM
  • Polishing of MAbs

Applications

  • Application
    Resin screening and process optimization

Compliance Information

  • Quality Standards
    • CoA
    • RSF (upon request)

Dimensions

  • Bead Size
    50 µm
  • Bed Height
    50 mm
  • Dimensions
    5 x 50 mm

General Specifications

  • Flow Rate
    ≥ 300 cm/h with ≤ 3 barg
  • Resin Format
    Pre-packed column

Materials of Construction

  • Base Matrix
    Ceramic Beads
  • Materials of Construction
    Polypropylene

Operating Conditions

  • Operating Pressure
    < 3 barg (44psi)
  • pH Stability
    1 to 14 (short term), 2 to 12 (long term)

Physicochemical Information

  • Bed Volume
    1 mL
  • Ligand
    Quaternary amine
  • Ligand Density
    > 250 µeq/mL
  • Reference Protein
    Bovine serum albumin (BSA)
  • Typical Dynamic Binding Capacity 10% per mL
    > 85 mg/mL BSA

Product Information

  • Brand
    Q Ceramic HyperD® F
  • Pack Size
    1 column per pack
  • Resin Delivery Condition
    20% EtOH/150 mM NaCl
  • Resin Type
    Strong anion exchanger
  • What you receive
    • 1 column
    • Instruction for use

Storage Conditions

  • Storage Conditions
    20% EtOH/1M NaCl