Single-use multi-column chromatography solution for use in good manufacturing practice (GMP) production suites where UL certification is required. The system is designed for applications where bioreactor batches exceed 1,000 L.

  • Highly efficient resin utilization
  • 3 to 5-fold increase in productivity
  • Easy-to-install flow kits (less than 30 minutes)

Item No.: 

*Custom/bulk order quotes are provided within 72 hours of request.

The Resolute® BioSMB 350 system is a multi-column chromatography solution for biopharmaceutical purification applications at clinical and commercial manufacturing scales. This single-use, integrated system is specifically designed to allow users to drive efficiency and cost savings into their chromatography operations without impacting purification performance or product quality.


  • Application
    • mAb Purification  
    • Antibody Purification  
    • Polishing  
    • Capture  
    • Affinity  
    • Large Molecules  
  • Application Area
    • Clinical manufacturing  
    • Commercial manufacturing  

Compliance Information

  • GMP Compliance
  • IP Rating
    IP54 for control tower  


  • Dimensions WxDxH
    2.7×1.4×2.2 m (106×55×87 inch)  

General Specifications

  • Temperature Range
    4 – 40 °C  

Operating Conditions

  • Maximum Operating Pressure
    4 bar  

Power Requirements

  • Line Voltage
    208 VAC 50 | 60 Hz  
  • Power Requirements
    32A – 15kW  

Product Information

  • Brand


  • Volume
    30 – 350 L/h  
  • Resolute® BioSMB Additional 80 Pump Module

    The Resolute® BioSMB 80 pump module is an add-on module for the Resolute® BioSMB 350 system to enable the use of Resolute® BioSMB 80 flow kits, increasing the flexibility of the main system.