Sartocon® Slice Disposable Cassette | PES | 8kDa | 0.1m²
Choose your Sartocon® and Sartocube® | TFF Ultrafiltration | Cassettes
Sartocon® Polyethersulfone TFF cassettes are well established in the biotechnological and pharmaceutical industry. The PES membrane is a stable polymer that features a broad pH and temperature range. Membrane regeneration, storage and depyrogenation can be accomplished by using NaOH even at elevated temperatures.
Sartocon® cassettes are self-sealing, feature low extractables and the enlarged feed and retentate ports lower system pressure drops.
Sartocon® cassettes are ideally combined with Sartorius Sartocon holders and systems.
Polyethersulfone Membrane
Polyethersulfone (PES) membrane is an established membrane polymer that is well suited to any biopharmaceutical process applications. PES membrane is a stable polymer that can operate in a broad pH and temperature range and withstand aggressive cleaning cycles.
Flow Channel Geometry
The Sartocon® family is available in two flow channel geometry versions. E-Screen filters are dominantly used for protein concentrations up to above 20% as well as viscosity conditions greater than 3 cp. ECO-Screen devices mainly used for water based protein solutions of below 20% protein concentration as well as lower than 3 cp viscosity allow economical optimized filtration runs.
Available Sizes and Cut-Offs
Sartorius Sartocon® and Sartocube® TFF cassettes are available for pilot- and production scale, and in Sartocon® Slice as well as Sartocon® Slice 200 format for reduced volume handling.
Cut-Offs:
E-screen: 1 | 5 | 8 | 10 | Albumin | 30 | 50 | 100 | 300 kDa
ECO screen: 10 | 30 | 100 | 300 kDa
Regulatory Compliance
All product contact materials have passed the current USP Biological Test and Cytotoxicity Test. All materials are BSE and TSE free. The filtrate meets or exceeds the currently valid USP and EP for sterile Water for Injection, with respect to extractable substances, oxidizable substances and Bacteria Endotoxins.
Applications
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IndustryPharma / Biotech
Compliance Information
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Bacterial Endotoxins< 0.18 EU/mL as determined by the LAL test
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Biological ReactivityAll materials of this filter element meet the requirements of the current USP Biological Reactivity tests <88> for plastics Class VI (Systemic Injection, Intracutaneous and Implantation tests).
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ExtractablesThe total amount of extractables is well below the limits established by the current USP unter "Sterile Water for Injection".
Dimensions
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Filtration Area0.1 m²
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Flow Channel GeometryProtein conc. >20% /or viscosity above.3cp
General Specifications
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Cassette FormatSlice Disposable
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Filter ClassUltrafilter
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Filter ConfigurationSlice Disposable Cassette
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Filter FormatCassettes
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Ultrafilter8 kD Polyethersulfone Ultrafilter Membrane
Materials of Construction
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Integral FramePolyvinylidene fluoride (PVDF)
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Membrane MaterialPolyethersulfone (PES)
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Sealing CompoundSilicone White (High chemical resistance)
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SpacerPolypropylene (PP)
Operating Conditions
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Maximum Inlet Pressure4 bar
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pH StabilitypH 1 – 14
Physicochemical Information
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MWCO8 kDa
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Non-Fiber ReleasingThis filter product complies with the title 21 of the Code of Federal Regulations (CFR), section 210.3(b)(6) and 211.72.
Product Information
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BrandSartocon®
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Pack Size1
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Type8 kDa | Polyethersulfone