SDR HyperD® for solvent detergent removal in bioprocessing features high capacity for a wide range of detergents and secures high recovery of protein. The resin is composed of silica beads whose pores are filled with a three-dimensional crosslinked hydrophobic polymer. The small pore size, particle size distribution (40 to 100 μm), and hydrophobic nature of the chemical groups make SDR HyperD resin ideal for detergent removal.
Features and Benefits
- High dynamic binding capacity for many different detergents
- High recovery for proteins
- Ideal tool for both removing solvent and detergent
- Stable in acid, polar organic, and oxidizing solutions
Applications
- Binds detergent molecules typically used in viral inactivation processes [i.e., Tri-n-Butyl Phosphate (TnBP) and Triton X-100]
- Removal of both ionic and zwitter ionic detergents from biological solutions
Applications
-
ApplicationPreparative protein purification
Compliance Information
-
Quality Standards
-
CoA
- RSF
-
CoA
Dimensions
-
Bead Size70 µm
General Specifications
-
Flow Rate100-600 cm/h
-
Resin FormatBulk resin
Materials of Construction
-
Base MatrixSilica beads
Operating Conditions
-
Operating Pressure< 3 barg (44psi)
-
pH Stability2 to 12 (working pH)
Physicochemical Information
-
LigandHydrophobic polymer
-
Reference ProteinTriton
-
Typical Dynamic Binding Capacity 10% per mL> 90 mg/mL Triton
Product Information
-
BrandSDR HyperD®
-
Pack Size1
-
Pack Volume10 L
-
Resin Delivery Condition20% EtOH
-
Resin TypeHydrophobic
-
What you receive1 bottle resin, instructions
Storage Conditions
-
Storage Conditions20% EtOH