pPLUS^® AAV-Helper is a novel plasmid helper designed for AAV production. This plasmid has been optimized for triple transfection of HEK293 cells in suspension. The use of pPLUS^® AAV-Helper leads to enhanced AAV titers and improved AAV particles quality.

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Item No.:: 101000183
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Overview

This plasmid is the outcome of an extensive R&D program based on our proprietary DNA assembly technology (the eZyvec® technology) aiming at exploring the synergies of multiple genetic features to improve the infectivity (measured in TU/mL) and quality (full/empty ratio) of the viral particles obtained through triple transfection of HEK293 cells in suspension with FectoVIR^®-AAV. They are readily available as an off-the-shelf product.

Key Benefits:

Optimized for AAV Production with FectoVIR®-AAV: Increased AAV titers and AAV particles quality when used together with FectoVIR®-AAV

Versatile: Suitable for use with various cell lines and production of several AAV serotypes.

Compatible: With PEIpro® and other transfection reagents, suitable for use with various cell lines and production of several AAV serotypes.

Adapted for your Projects from Research to Large Scale Manufacturing: Three packsize of Research Grade available, HQ and GMP Grade. GMP Grade coming soon (2025).

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