FectoVIR®-AAV is a novel generation of synthetic transfection reagent specifically developed for industrial scale production of recombinant AAV (rAAV) in both suspension and adherent HEK-293 derivative cell systems

Amount of Reagent
Item No.: 
101000187

*Custom/bulk order quotes are provided within 72 hours of request.

Lentiviral vectors are recognized to be the carrier of choice for allogenic or autologous cell therapies (such as CAR-T) because of its capacity to permanently integrate viral genome into host cell DNA. To produce those vectors, cell therapy producers generally use a transient transfection system that is scaled-up during process development phases. FectoVIR®-LV is the next generation of transfection reagent, free of animal component, designed to improve LV productivity in HEK-293 cell systems. FectoVIR®-LV is made for large scale manufacturing with reduction of the complexation volume and increased complex stability. The FectoVIR®-LV benefits allow to increase number of doses produced per batch to treat more patient, while decreasing LV manufacturing costs. 

Take advantage of the complementary DOE service to fast-track optimization of lentivirus production with FectoVIR®-LV. 

Key Benefits:

  • Productivity: Reach the highest Lentiviral vectors titers in suspension systems.
  • Cost-Effectiveness: Reduce your cost per batch with high titers and low DNA consumption.
  • Scalability: Produce at large scale with low complexation volume and long complex stability.
  • Time-Saving: Use DOE service to help you optimizing your process in a record time.

Applications

  • Application
    Lentiviral vectors (LV) manufacturing using HEK-293 derivative cells cultivated in suspension  

Biological Information

  • Number of transfections
    100 mL of FectoVIR®-LV transfection reagent is sufficient to transfect on average 50 L of cell culture (using standard conditions)  

Compliance Information

  • Product Documentation
    • Protocol   
    • Certificate of Analysis   
    • Non-hazardous product statement  
    • Certificate of origin   

General Specifications

  • Amount of Reagent
    FectoVIR®-LV 1 mL  

Storage Conditions

  • Storage Conditions
    5 °C ± 3 °C