HyperCel STAR AX is an industry-scalable anion exchange chromatography resin designed for high productivity protein capture at moderate or higher salt conductivity (2 to 15 mS/cm), typical of undiluted biological feedstocks (e.g. mammalian cell culture supernatants, E. coli feedstock, plasma, etc.).
HyperCel STAR AX pre-packed columns are designed to simplify resin screening and selection, making them ideal for optimizing process steps. The RoboColumn® format is particularly suited for high throughput process development (HTPD), allowing for efficient and streamlined purification processes.
Features and Benefits
- High dynamic binding capacity (DBC) at short residence time (2 minutes or lower)
- Direct capture of protein from undiluted feedstock at moderate or high conductivity
- Excellent flow rate properties for fast feedstock processing
- Distinctive selectivity, consistent in a broad conductivity range (2 – 15 mS/cm)
- Enhanced process economics
- Manufactured at large scale and to meet the demands of commercial users and regulatory authorities
Applications
- Direct capture of recombinant proteins, mono- and poly-clonal antibodies, plasma derivatives
- Direct Capture of Albumin from Undiluted Plasma
- Early Removal of CHOPs before Protein A Capture of a Monoclonal Antibody (MAb)
