CIMmultus® r-Protein L-80mL 1.3µm

Tech Support

CIMmultus® r-Protein L columns are used for fast and efficient purification of a wide range of antibodies and antibody fragments such as Fabs, single-chain variable fragments (scFv) and domain antibodies (Dabs).

  • Has the ability to bind to a wide range of immunoglobulins without being species-specific
  • Protein L offers an advantage over proteins A and G as it binds to kappa light chains regardless of heavy chain subclass

Notice: CIMmultus® r-Protein L columns are non standard products. Provided on request.

Item No.: 
611.1021-1.3
*Custom/bulk order quotes are provided within 72 hours of request.
CIMmultus® r-Protein L-80mL 1.3µm

CIMmultus® r-Protein L columns are used for fast and efficient purification of a wide range of antibodies and antibody fragments such as Fabs, single-chain variable fragments (scFv) and domain antibodies (Dabs).

  • Has the ability to bind to a wide range of immunoglobulins without being species-specific
  • Protein L offers an advantage over proteins A and G as it binds to kappa light chains regardless of heavy chain subclass

Notice: CIMmultus® r-Protein L columns are non standard products. Provided on request.

Item No.:
611.1021-1.3

Overview

Specifications

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CIMmultus® Monoliths are reusable chromatography devices for scalable high-resolution purification of complex biological samples. Inside the custom designed housing is a single piece stationary phase with homogeneous channel size and surface chemistry. This stationary phase is designed to simplify method transfer from development into production.

They can be used as single-use disposable or multi-use columns, and they are available in various volume ranges – from 1mL for screening and method development purposes up to 40L for industrial manufacturing.

r-Protein L features

  • Has the ability to bind to a wide range of immunoglobulins without being species-specific
  • Protein L offers an advantage over proteins A and G as it binds to kappa light chains regardless of heavy chain subclass

Benefits

  • Very fast processes by convective mass transport – resolution independent of flow
  • Ready to use columns
  • High-capacity for large molecules due to fully accessible void volume in the channels
  • Laminar flow minimizes shear stress resulting in high yields

Applications

  • Application
    • Preparative protein purification
    • Preparative Applications
    • Protein and mAb production

Compliance Information

  • GMP Compliance
    non-cGMP

Connections (Physical)

  • Connector(s)
    TC 1" (25 mm), 3 mm ID bore

Dimensions

  • Channel Size
    1.3 µm
  • Column Tube Length
    110 mm
  • Inner Diameter
    15 mm
  • Outer Diameter
    34 mm

Features

  • Reusable
    Yes

General Specifications

  • Flow Rate
    8–400 mL/min | 6–300 cm/h | 0.1–5 CV/min

Materials of Construction

  • Materials of Construction
    Poly(butyl methacrylate -co- ethylene dimethacrylate)

Operating Conditions

  • Maximum Operating Pressure
    2.0 MPa | 20 bar | 290 psi

Physicochemical Information

  • Bed Volume
    80 mL

Product Information

  • Brand
    CIMmultus®
  • Package Type
    Individually Packed

Volume

  • Volume
    80 mL