Flexsafe® RM 2L perfusion (3 pcs)

Tech Support
Flexsafe® RM 2L perfusion (3 pcs) Flexsafe® RM 2L perfusion (3 pcs)
 

The Flexsafe® RM single-use bioreactor bags (sizes from 2 L to 200 L) fit to the Biostat® RM bioreactors. The product is based on rocking motion mixing technology which is ideal for cell cultivation with low shear stress.

Perfusion bags are available in two versions:

A) With an integrated 1.2 μm perfusion membrane (PES). The membrane is fixed at the bottom of the bag, forming a compartment for removal of cell free media. The wave created by the agitation moves over the surface of the membrane, thereby flushing the membrane with every rocking motion. This innovative and patented design ensures low fouling and long cultivation times.

B) ATF perfusion bags are designed for convenient connection.

Item No.: 
DFP002L--SM
Availability: 

*Custom/bulk order quotes are provided within 72 hours of request.

Choose your Flexsafe® RM

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  • Integrates single-use pH and DO sensors
  • Excellent cell growth and robustness
  • Integrated BioPAT® Viamass sensor for viable biomass measurement
  • Customized bag designs possible
  • Delivered gamma-irradiated and ready to use

  • The optical bag is mainly used for an advanced applications. It can also be scaled up to our Biostat STR® single-use stirred tank bioreactor equipped with Flexsafe STR® bags. Flexsafe® RM bags are proven for a broad range of different cell lines incl. CHO, NS0, SF9, E.coli and mesenchymal stem cells. They are available in six different sizes supporting working volumes from 200 mL up to 100 L. Standard designs are available from stock.

Applications

  • Application
    • Mammalian cell culture
    • Insect cell culture
    • Microbial Fermentation
    • Low molecular weight binding
    • Shear-stress-sensitive cells such as stem cells
  • Application Area
    Preclinical and clinical studies

Compliance Information

  • Biocompatibility (USP Class VI)
    • USP Class VI and | or ISO10993 conformity
    • USP<85>
    • USP<87> | ISO10993-5
    • USP<88>
    • USP<788>

Components

  • Gas Filters
    HEPA rated hydrophobic filter

Connections (Physical)

  • Connector(s)
    • Female | Male Luer
    • Female | Male MPC
    • Clave® connector
    • Opta® SFT Connector

Features

  • Device/Instrument Compatibility
    • Biostat® RM 20 | 50 L
    • Biostat® RM TX
  • Sensors
    • Optical DO
    • Optical pH

General Specifications

  • pH Range
    pH 6.0 – 8.0

Materials of Construction

  • Film Material
    S80
  • Membrane
    Polyethersulfone (PES) 1.2 μm

Operating Conditions

  • Operating Conditions - Temperature
    16 – 40°C (specified by the hardware)

Physicochemical Information

  • Pressure Range
    Operation pressure: 6 mbar [g] - 30 mbar [g]

Product Information

  • Brand
    Flexsafe® RM

Usage Protocols

  • Gamma Irradiation
    ≥25 kGy

Volume

  • Working Volume
    0.2 – 1L