Choose your CIMac™
CIMac™ Analytical Columns are short-bed high-performance monolithic columns offering all the advantages of CIM® monolithic technology. Their small volume and short column length allow the operation at high volumetric flow rates enabling them to receive the information about the product quantity and purity in just a few minutes. Hence, the CIMac™ Analytical Columns can be effectively used for the in-process and final control of various samples from different purification process steps.
CIMac PrimaS® plays a key role within BIA’s family of high-performance chromatography products for analysis and purification of mRNA. Its positive charge confers it some anion exchange behavior, but hydrogen bonding makes its selectivity entirely distinct from traditional anion exchangers.
PrimaS® features:
Multimodal chromatography ligand that combines elements of hydrogen bonding with anion exchange chromatography
Unique selectivities in many important product areas
Supports purification of single-stranded RNA at ambient temperature
Applications
-
ApplicationAnalytical Columns
Connections (Physical)
-
Connector(s)10-32 UNF coned port, 0.0625" OD tubing connection
Dimensions
-
Channel Size2 µm
-
Diameter5.2 mm
-
Length4.95 mm
Features
-
ReusableYes
General Specifications
-
Flow Rate0.2 – 3 mL/min | 1 – 15 cm/min | 2 – 30 CV/min
Materials of Construction
-
Materials of ConstructionPoly(glycidyl methacrylate -co- ethylene dimethacrylate)
Operating Conditions
-
Maximum Operating Pressure15 MPa | 150 bar | 2175 psi
-
Recommended Operating Temperature2 °C (36 °F) to 25 °C (77 °F)
-
pH StabilityWorking range 2–11, cleaning in place 1–13
Physicochemical Information
-
Bed Volume0,1 mL
-
LigandMultimodal (anion exchange-hydrogen bonding)
Product Information
-
BrandCIMac™
Storage Conditions
-
Storage Conditions20% EtOH