Sartoflow® Expert SU
Efficient and Versatile - The TFF System from PD to Pilot
One-skid solution is safe and efficient
A single system streamlines three steps (mixing, filtration, UF/DF) and eliminates product transfer.
Fully scalable single-use solution
Versatile cGMP single-use TFF system provides a seamless transition from 1-20 L scale (i.e. 2 - 100 L starting volume).
Flexible process sequencing
The system has the flexibility to accommodate different sequences of process steps.
Reduced bioburden, ready-to-use system
A gamma-irradiated closed-loop system prevents leaks and eliminates cleaning and validation efforts.
- Item No.:
- SFEXPERTSU
Choose your Sartoflow® Tangential Flow Filtration Systems
3-In-1 Single Use Approach
The Sartoflow® Expert SU is a flexible fully automated single-use TFF system for process development up to pilot-scale manufacturing, running filtration sizes from 0.14 up to 1.4 m² in 1-20 L scale.
It streamlines up to three process steps - mixing, ultrafiltration/diafiltration and sterile-grade filtration in a robust fully single-use closed loop, increasing operator safety, product integrity and process quality.
The Sartoflow® Expert SU features an intuitive visual and software-based guidance to ensure the correct installation of the single-use components. Several peristaltic pumps are available for automated transfer and addition of process fluids.
Applications
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Application
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Purification of mAbs, ADC, vaccines, viral vectors, and recombinant proteins
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Concentration
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Microfiltration
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Ultrafiltration
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Desalting
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Buffer Exchange
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Single Use Processing
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Antibody Purification
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Protein Concentration
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DNA Concentration
- mRNA concentration
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Purification of mAbs, ADC, vaccines, viral vectors, and recombinant proteins
Connections (Physical)
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ConnectorsAseptic, MPC, and Luer connectors on single-use flow kits and bags
Dimensions
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Dimensions WxDxHBase Unit: 1,430 x 755 x 1,755 mm (nominal) With 2nd bag holder: 1,875 x 755 x 1,755 mm (nominal)
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Membrane Area0.14, 0.28, 0.42, 1.4 m²
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Tube Size (ID – OD)3/8"
Features
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DisplayColored Touchscreen
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Including Control StationYes
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Sensors
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pH
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Conductivity
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Pressure
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Flow
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Temperature
- UV
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pH
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Temperature ControlRefrigerated and heated
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Temperature SensorpT100
General Specifications
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Cassette Format
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Sartocon® SCU
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Sartocube® SCU
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Sartocon Cassettes
- Sartocube Cassettes
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Sartocon® SCU
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Filter FormatCassettes
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Pump OutputUp to 900 L/h
Materials of Construction
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Recirculation Vesselsingle-use
Operating Conditions
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Maximum Operating Pressure4 bar | 58 psi
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Minimum Operating Volume~ 600 mL
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Recommended Operating TemperatureUp to 40 C°
Power Requirements
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Power Requirements100 - 120 V, 50/60 Hz, 9A220 - 240 V, 50/60 Hz, 5A
Product Information
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BrandSartoflow®
Volume
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Bag Volume1-20 L (20 L 3D mixing bag)
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Hold-up Volume~400 mL
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Recirculation Vessel Volume1-20 L (20 L 3D mixing bag)
Weight
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Total Weight450 kg
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 10 kDa
- Effective Filtration Area: 0.42 m²
- Membrane Material: Hydrosart®
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 30 kDa
- Effective Filtration Area: 0.28 m²
- Membrane Material: Hydrosart®
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 300 kDa
- Effective Filtration Area: 0.42 m²
- Membrane Material: Hydrosart®
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 30 kDa
- Effective Filtration Area:0.14 m²
- Membrane Material: Polyethersulfone
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 100 kDa
- Effective Filtration Area: 1.4 m²
- Membrane Material: Hydrosart®
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 100 kDa
- Effective Filtration Area: 0.14 m²
- Membrane Material: Hydrosart®
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 100 kDa
- Effective Filtration Area: 0.42 m²
- Membrane Material: Hydrosart®
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 10 kDa
- Effective Filtration Area: 0.14 m²
- Membrane Material: Hydrosart®
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 30 kDa
- Effective Filtration Area:0.42 m²
- Membrane Material: Polyethersulfone
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 10 kDa
- Effective Filtration Area:0.42 m²
- Membrane Material: Polyethersulfone
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 300 kDa
- Effective Filtration Area: 1.4 m²
- Membrane Material: Hydrosart®
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 300 kDa
- Effective Filtration Area:0.14 m²
- Membrane Material: Polyethersulfone
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 300 kDa
- Effective Filtration Area: 0.28 m²
- Membrane Material: Hydrosart®
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 100 kDa
- Effective Filtration Area: 0.28 m²
- Membrane Material: Hydrosart®
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 10 kDa
- Effective Filtration Area:0.14 m²
- Membrane Material: Polyethersulfone
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 30 kDa
- Effective Filtration Area:0.28 m²
- Membrane Material: Polyethersulfone
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 100 kDa
- Effective Filtration Area:0.42 m²
- Membrane Material: Polyethersulfone
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 30 kDa
- Effective Filtration Area: 0.42 m²
- Membrane Material: Hydrosart®
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 300 kDa
- Effective Filtration Area:0.28 m²
- Membrane Material: Polyethersulfone
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 100 kDa
- Effective Filtration Area:0.28 m²
- Membrane Material: Polyethersulfone
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 30 kDa
- Effective Filtration Area:1.4 m²
- Membrane Material: Polyethersulfone
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 10 kDa
- Effective Filtration Area:1.4 m²
- Membrane Material: Polyethersulfone
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 30 kDa
- Effective Filtration Area: 0.14 m²
- Membrane Material: Hydrosart®
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 300 kDa
- Effective Filtration Area:1.4 m²
- Membrane Material: Polyethersulfone
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 300 kDa
- Effective Filtration Area: 0.14 m²
- Membrane Material: Hydrosart®
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 300 kDa
- Effective Filtration Area:0.42 m²
- Membrane Material: Polyethersulfone
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 30 kDa
- Effective Filtration Area: 1.4 m²
- Membrane Material: Hydrosart®
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 10 kDa
- Effective Filtration Area:0.28 m²
- Membrane Material: Polyethersulfone
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 10 kDa
- Effective Filtration Area: 0.28 m²
- Membrane Material: Hydrosart®
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 10 kDa
- Effective Filtration Area: 1.4 m²
- Membrane Material: Hydrosart®
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 100 kDa
- Effective Filtration Area:1.4 m²
- Membrane Material: Polyethersulfone
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 100 kDa
- Effective Filtration Area:0.14 m²
- Membrane Material: Polyethersulfone
- Channel Design: ECO
- Connectors: AseptiQuik®
Fully single-use TFF (SUTFF) flow kits reduce preparation times, the need for cleaning validation and the risk of cross-contamination between different molecule productions. Thus enabeling:
- Faster change-over between different products
- More efficient and productive system use
- Increased facility flexibility
- Increased productivity per sqm manufacturing space
Sartolon filters are designed for broad chemical compatibility for specific applications in the pharmaceutical and chemical industry. The double-layer design leads to superior filtration performance compared to other nylon membrane filters and thereby allows more economical design of your filtration process. Sartolon filter elements are ideal for filtration of a broad range of solvents and solvent-containing liquids as well as oily formulations.