Tangential Flow Filtration (TFF) (764)

Product Family

Sartoflow® Tangential Flow Filtration Systems

Sartorius offers flexible tangential flow filtration (TFF) systems for process development and clinical trials up to commercial production batches.
The TFF portfolio can flex to accommodate individual requirements, with a range of options that includes cost-efficient multi-use systems or closed systems with single-use flow kits for bioburden reduced processing.

Benchtop to production scale from 100 mL to 200 L
Working membrane sizes from 10 cm² to 10 m²
Single-use and multi-use
Highly- to fully automated
Compliancy to cGMP available
Modular standard systems allow shorter lead times

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Product Family

Sartocon® and Sartocube® | TFF Ultrafiltration | Cassettes

Membrane Materials: Hydrosart® or Polyethersulfone
Effective Filtration Areas: 0.02m² - 3.5m²
Cut-Offs: 1 - 300 kDa
Screen Types: E-Screen or ECO Screen

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Product Family

Sartocon® and Sartocube® | TFF Microfiltration | Cassettes

Membrane Materials: Hydrosart® or Polyethersulfone
Effective Filtration Areas: 0.02m² - 3m²
Pore Sizes: 0.1µm | 0.2µm | 0.45µm
Screen Types: Open Channes | Wide Spacer

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Product Family

Ambr® Crossflow

Study factors for manufacturability
Collect important information about the behaviour of the molecules in downstream processing already in an early stage
Automated, parallel trials
Up to 16 channels can be managed by one control station
Lowest process volumes
Small scale screening with 10 cm² membrane area | 5 mL recirculation volume
Flexibility of two different process scales
Mid-scale screening is also possible with Sartocon® Slice 50 which has 50 cm² membrane area

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Product Family

Sartoflow® Single-Use Flow Kits

For Sartoflow® TFF Systems:

3/8" Sartoflow® 150
3/8" Sartoflow® Expert SU
1/2" Sartoflow® 1000
1" Sartoflow® 4500

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Product Family

Sartocon® and Sartocube® | TFF Ultrafiltration | Self-Contained Units

Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use

Cut-Offs: 10 - 300 kDa

Effective Filtration Areas: 0.14 - 14m²
Membrane Material: Hydrosart® or Polyethersulfone

Channel Design: ECO

Connectors: AseptiQuik®

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Product Family

Single-use Line

The Hollow Fiber TFF Modules | Single-use Line offer a true single-use tangential flow filtration solution. A broad variety of different pore sizes and molecular weight cut-offs (MWCO) ensure a suitable solution for a wide range of processes. The scalability ranging from Lab- over Pilot- up to Process-scale increases flexibility in each stage of production. Hollow Fiber TFF Modules | Single-use are delivered gamma irradiated, fully integrity tested and therefore ready-to-use. Since, no cleaning is required you can save valuable time.

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Product Family

Steamer Line

The Steamer Line Hollow Fiber TFF Modules are designed for perfusion and aseptic applications. They are delivered gamma irradiated and ready to use and can be autoclaved.

Self-contained units

Autoclavable

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