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HA Ultrogel® - 500 mL

Tech Support Documents
HA Ultrogel® - 500 mL HA Ultrogel® - 500 mL
 

HA Ultrogel® is a composite material of cross-linked agarose and microcrystalline hydroxyapatite enclosed in the agarose matrix. The material shows mixed mode functionality based on cation exchange and metal affinity in the hydroxyapatite structure. A wide variety of applications include separation of proteins, peptides and nucleic acids, from laboratory to production scale.

  • Bulk resins offer flexibility and scalability for large-scale bioprocessing
  • Allow for customized column packing to meet specific process requirements
Pack Volume
Price (USD)
$1,770.00
Item No.: 
24775-017
*Custom/bulk order quotes are provided within 72 hours of request.
HA Ultrogel® - 500 mL
HA Ultrogel® - 500 mL

HA Ultrogel® is a composite material of cross-linked agarose and microcrystalline hydroxyapatite enclosed in the agarose matrix. The material shows mixed mode functionality based on cation exchange and metal affinity in the hydroxyapatite structure. A wide variety of applications include separation of proteins, peptides and nucleic acids, from laboratory to production scale.

  • Bulk resins offer flexibility and scalability for large-scale bioprocessing
  • Allow for customized column packing to meet specific process requirements
Price (USD):
$1,770.00
Item No.:
24775-017

Overview

Specifications

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HA Ultrogel® resin is a hydroxyapatite agarose composite resin for the separation of biomolecules from research and to manufacturing scale. Hydroxyapatite chromatography is considered to be a “pseudo-affinity” chromatography, or “mixed mode” ion exchange. It has proven to be an effective purification mechanism in a variety of processes, providing biomolecule selectivity complementary to more traditional ion exchange or hydrophobic interaction techniques.

Bulk resins are available in various quantities to support different scaling processes, ensuring flexibility and adaptability. Perfect for large-scale purification processes.

Features and Benefits

  • Unique selectivity and separation mechanism, complementary to traditional IEX and HIC
  • Protein purification in neutral, non-denaturating conditions
  • High porosity, easy cleaning

Applications

  • Purification of human serum proteins
  • Purification of basic proteins, of phosphate-dependent proteins and enzymes, and of DNA-dependent enzymes
  • Vaccine purification processes, e.g. Bordetella pertussis toxin
  • Separation of plant proteins such as lectins, glycoproteins, glycosidases, phospholipidases, sulfohydrolases, sphingomyelinases, transferases, trehalases and kinases

Applications

  • Application
    Preparative protein purification

Compliance Information

  • Quality Standards
    • CoA
    • RSF (upon request)

Dimensions

  • Bead Size
    60-80 µm

General Specifications

  • Flow Rate
    < 100 cm/h
  • Resin Format
    Bulk resin

Materials of Construction

  • Base Matrix
    Agarose

Operating Conditions

  • Operating Pressure
    < 2 barg (44psi)

Physicochemical Information

  • Ligand
    Hydroxyapatite
  • Reference Protein
    Cytochrome C
  • Typical Dynamic Binding Capacity 10% per mL
    > 7 mg/mL Cytochrome C

Product Information

  • Brand
    HA Ultrogel®
  • Pack Size
    1
  • Pack Volume
    500 mL
  • Resin Delivery Condition
    1M NaCl with 20% EtOH
  • Resin Type
    Mixed Mode cation exchanger
  • What you receive
    • 1 bottle
    • Instruction for use

Storage Conditions

  • Storage Conditions
    20% EtOH/1M NaCl