Sartoflow® Expert SU
Efficient and Versatile - The TFF System from PD to Pilot
One-skid solution is safe and efficient
A single system streamlines three steps (mixing, filtration, UF/DF) and eliminates product transfer.
Fully scalable single-use solution
Versatile cGMP single-use TFF system provides a seamless transition from 1-20 L scale (i.e. 2 - 100 L starting volume).
Flexible process sequencing
The system has the flexibility to accommodate different sequences of process steps.
Reduced bioburden, ready-to-use system
A gamma-irradiated closed-loop system prevents leaks and eliminates cleaning and validation efforts.
- Item No.:
- SFEXPERTSU
*Custom/bulk order quotes are provided within 72 hours of request.
Choose your Sartoflow® Tangential Flow Filtration Systems
3-In-1 Single Use Approach
The Sartoflow® Expert SU is a flexible fully automated single-use TFF system for process development up to pilot-scale manufacturing, running filtration sizes from 0.14 up to 1.4 m² in 1-20 L scale.
It streamlines up to three process steps - mixing, ultrafiltration/diafiltration and sterile-grade filtration in a robust fully single-use closed loop, increasing operator safety, product integrity and process quality.
The Sartoflow® Expert SU features an intuitive visual and software-based guidance to ensure the correct installation of the single-use components. Several peristaltic pumps are available for automated transfer and addition of process fluids.
Applications
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Application
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Purification of mAbs, ADC, vaccines, viral vectors, and recombinant proteins
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Concentration
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Microfiltration
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Ultrafiltration
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Desalting
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Buffer Exchange
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Single Use Processing
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Antibody Purification
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Protein Concentration
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DNA Concentration
- mRNA concentration
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Purification of mAbs, ADC, vaccines, viral vectors, and recombinant proteins
Connections (Physical)
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Connector(s)Aseptic, MPC, and Luer connectors on single-use flow kits and bags
Dimensions
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Dimensions WxDxHBase Unit: 1,430 x 755 x 1,755 mm (nominal) With 2nd bag holder: 1,875 x 755 x 1,755 mm (nominal)
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Membrane Area0.14, 0.28, 0.42, 1.4 m²
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Tube Size (ID – OD)3/8"
Features
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DisplayColored Touchscreen
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Including Control StationYes
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Sensors
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pH
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Conductivity
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Pressure
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Flow
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Temperature
- UV
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pH
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Temperature ControlRefrigerated and heated
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Temperature SensorpT100
General Specifications
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Cassette Format
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Sartocon® SCU
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Sartocube® SCU
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Sartocon Cassettes
- Sartocube Cassettes
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Sartocon® SCU
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Filter FormatCassettes
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Pump OutputUp to 900 L/h
Materials of Construction
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Recirculation Vesselsingle-use
Operating Conditions
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Maximum Operating Pressure4 bar | 58 psi
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Minimum Operating Volume~ 600 mL
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Recommended Operating TemperatureUp to 40 C°
Power Requirements
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Power Requirements100 - 120 V, 50/60 Hz, 9A220 - 240 V, 50/60 Hz, 5A
Product Information
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BrandSartoflow®
Volume
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Bag Volume1-20 L (20 L 3D mixing bag)
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Hold-up Volume~ 400 mL
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Recirculation Vessel Volume1-20 L (20 L 3D mixing bag)
Weight
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Total Weight450 kg
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 10 kDa
- Effective Filtration Area: 0.42 m²
- Membrane Material: Hydrosart®
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 30 kDa
- Effective Filtration Area: 0.28 m²
- Membrane Material: Hydrosart®
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 300 kDa
- Effective Filtration Area: 0.42 m²
- Membrane Material: Hydrosart®
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 30 kDa
- Effective Filtration Area:0.14 m²
- Membrane Material: Polyethersulfone
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 100 kDa
- Effective Filtration Area: 1.4 m²
- Membrane Material: Hydrosart®
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 100 kDa
- Effective Filtration Area: 0.14 m²
- Membrane Material: Hydrosart®
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 100 kDa
- Effective Filtration Area: 0.42 m²
- Membrane Material: Hydrosart®
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 10 kDa
- Effective Filtration Area: 0.14 m²
- Membrane Material: Hydrosart®
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 30 kDa
- Effective Filtration Area:0.42 m²
- Membrane Material: Polyethersulfone
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 10 kDa
- Effective Filtration Area:0.42 m²
- Membrane Material: Polyethersulfone
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 300 kDa
- Effective Filtration Area: 1.4 m²
- Membrane Material: Hydrosart®
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 300 kDa
- Effective Filtration Area:0.14 m²
- Membrane Material: Polyethersulfone
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 300 kDa
- Effective Filtration Area: 0.28 m²
- Membrane Material: Hydrosart®
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 100 kDa
- Effective Filtration Area: 0.28 m²
- Membrane Material: Hydrosart®
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 10 kDa
- Effective Filtration Area:0.14 m²
- Membrane Material: Polyethersulfone
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 30 kDa
- Effective Filtration Area:0.28 m²
- Membrane Material: Polyethersulfone
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 100 kDa
- Effective Filtration Area:0.42 m²
- Membrane Material: Polyethersulfone
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 30 kDa
- Effective Filtration Area: 0.42 m²
- Membrane Material: Hydrosart®
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 300 kDa
- Effective Filtration Area:0.28 m²
- Membrane Material: Polyethersulfone
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 100 kDa
- Effective Filtration Area:0.28 m²
- Membrane Material: Polyethersulfone
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 30 kDa
- Effective Filtration Area:1.4 m²
- Membrane Material: Polyethersulfone
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 10 kDa
- Effective Filtration Area:1.4 m²
- Membrane Material: Polyethersulfone
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 30 kDa
- Effective Filtration Area: 0.14 m²
- Membrane Material: Hydrosart®
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 300 kDa
- Effective Filtration Area:1.4 m²
- Membrane Material: Polyethersulfone
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 300 kDa
- Effective Filtration Area: 0.14 m²
- Membrane Material: Hydrosart®
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 300 kDa
- Effective Filtration Area:0.42 m²
- Membrane Material: Polyethersulfone
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 30 kDa
- Effective Filtration Area: 1.4 m²
- Membrane Material: Hydrosart®
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 10 kDa
- Effective Filtration Area:0.28 m²
- Membrane Material: Polyethersulfone
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 10 kDa
- Effective Filtration Area: 0.28 m²
- Membrane Material: Hydrosart®
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 10 kDa
- Effective Filtration Area: 1.4 m²
- Membrane Material: Hydrosart®
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 100 kDa
- Effective Filtration Area:1.4 m²
- Membrane Material: Polyethersulfone
- Channel Design: ECO
- Connectors: AseptiQuik®
- Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
- Cut-Off: 100 kDa
- Effective Filtration Area:0.14 m²
- Membrane Material: Polyethersulfone
- Channel Design: ECO
- Connectors: AseptiQuik®
Fully single-use TFF (SUTFF) flow kits reduce preparation times, the need for cleaning validation and the risk of cross-contamination between different molecule productions. Thus enabeling:
- Faster change-over between different products
- More efficient and productive system use
- Increased facility flexibility
- Increased productivity per sqm manufacturing space
Features & Benefits
- Bioburden reduced
- Chemical compatibility
- Spill-free process and disassembly
- Reduced hands-on time
- No cleaning and validation efforts
Features & Benefits
Bioburden reduced
Chemical compatibility
Spill-free process and disassembly
Reduced hands-on time
No cleaning and validation efforts
Features & Benefits
Bioburden reduced
Chemical compatibility
Spill-free process and disassembly
Reduced hands-on time
No cleaning and validation efforts
Key Facts
The Sartoflow® Expert SU media addtition flow kit enables up to three extra process media on Sartoflow® Expert SU TFF system.
Features & Benefits
Bioburden reduced
Chemical compatibility
Spill-free process and disassembly
Reduced hands-on time
No cleaning and validation efforts
- Effective Filtration Area: 0.2 m² | 2.2 ft²
- Pore Size: 0.45 µm prefilter | 0.2 µm final filter
- Membrane Material: Polyamide (Nylon)
- Connectors: Inlet: Sanitary ¾“ | Outlet: Sanitary ¾“
- Sterilization: Delivered sterile (Autoclaved)
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Connector explanation:
O = Hose Barb ½“ | S = Sanitary 1 ½“ | F = Sanitary ¾“