Sartoclean® CA | Sartoscale 47 | 0.8µm | 3pc.

Sartoclean® CA Prefiltration Filters

Sartoclean® CA filter elements provide efficient prefiltration for biopharmaceutical liquids, combining particle removal with bioburden reduction. The double-layer cellulose acetate membrane supports high product recovery and economical, stable processing across scales.

Key Features

• Double-Layer Construction: Two cellulose acetate layers increase dirt holding capacity and throughput, reducing changeouts and helping maintain stable flow over longer cycles.
• Low Adsorption Membrane: Cellulose acetate shows very low non-specific binding, which helps maximize protein yield and preservative recovery in sensitive formulations.
• Robust At High Differential Pressure: Mechanical and thermal resistance support operation up to 5 bar differential pressure, sustaining performance in demanding unit operations.
• Scalable Portfolio: Various formats with multiple pore sizes enable precise sizing from development to commercial manufacturing.
• Regulatory Compliance: Manufactured to meet non-pyrogenic and non-fiber releasing requirements and supported by comprehensive documentation for qualification.
  

Applications

• Plasma fractions
• Vaccines
• Purified protein solutions
• mAb
• Diagnostics
• Purified protein solutions
• Biological fluids
• Solutions containing preservatives
  

Benefits

• High Product Recovery: Very low non-specific adsorption limits product loss, supporting yield for plasma proteins, vaccine antigens, and purified protein solutions.
• Fewer Filter Changeouts: High throughput and strong particle loading capacity reduce filter replacements, helping shorten process time and labor.
• Stable, Predictable Flow: Consistent clarification improves upstream stability and supports downstream steps by reducing turbidity and particulate burden.
• PFAS: Made without intentionally using PFAS compounds.
• Economic Filtration: Efficient prefiltration lowers overall filter consumption and helps optimize cost per batch while maintaining process performance.
• Easy Scale-Up: Common materials and formats across the range simplify technology transfer from process development to production with predictable results.