CIMmultus® QA 4000 mL Monolithic Column (6 μm)

Tech Support Documents
CIMmultus® QA 4000 mL Monolithic Column (6 μm)
 

CIMmultus® is a unique and industry-proven line of pre-packed chromatographic monolithic columns featuring large flow-through channels, which make them ideal for purifying large biomolecules such as viruses (AAV, adenovirus, lentivirus, influenza, bacteriophages), nucleic acids (mRNA, pDNA), virus-like particles and exosomes.

Without the need for column packing, CIMmultus® columns are ready for use out of the box.

Available in:

  • Varied monolith volumes
  • Wide range of CIM® chemistries
  • Differing channel sizes
GMP Compliance
Volume
Channel Size
Item No.: 
BIA-1014.5113-6
*Custom/bulk order quotes are provided within 72 hours of request.
CIMmultus® QA 4000 mL Monolithic Column (6 μm)
CIMmultus® QA 4000 mL Monolithic Column (6 μm)

CIMmultus® is a unique and industry-proven line of pre-packed chromatographic monolithic columns featuring large flow-through channels, which make them ideal for purifying large biomolecules such as viruses (AAV, adenovirus, lentivirus, influenza, bacteriophages), nucleic acids (mRNA, pDNA), virus-like particles and exosomes.

Without the need for column packing, CIMmultus® columns are ready for use out of the box.

Available in:

  • Varied monolith volumes
  • Wide range of CIM® chemistries
  • Differing channel sizes
Item No.:
BIA-1014.5113-6

Overview

Specifications

Choose your CIMmultus®

See more products

CIMmultus® Monoliths are reusable chromatography devices for scalable high-resolution purification of complex biological samples. Inside the custom-designed housing is a single-piece stationary phase with homogeneous channel size and surface chemistry. This stationary phase is designed to simplify method transfer from development into production.

Features

  • Available with a wide range of chemistries
  • Various channel size options
  • Scalable from 1 mL to 40 L
  • Single batch use or multiuse
  • cGMP compliant

Benefits

  • Very fast processes by convective mass transport – resolution independent of flow
  • Ready to use columns
  • High-capacity for large molecules due to fully accessible void volume in the channels
  • Laminar flow minimizes shear stress resulting in high yields

Applications

  • Application
    Preparative Applications

Compliance Information

  • GMP Compliance
    non-cGMP

Connections (Physical)

  • Connector(s)
    TC 1" (25 mm), 8 mm ID bore

Dimensions

  • Channel Size
    6 µm
  • Column Tube Length
    205 mm
  • Inner Diameter
    255 mm
  • Outer Diameter
    300 mm

Features

  • Reusable
    Yes

General Specifications

  • Flow Rate
    400–12000 mL/min | 13–404 cm/h | 0.1–3 CV/min

Materials of Construction

  • Materials of Construction
    Poly(glycidyl methacrylate -co- ethylene dimethacrylate)

Operating Conditions

  • Maximum Operating Pressure
    0.5 MPa | 5 bar | 70 psi
  • Recommended Operating Temperature
    4 °C (39 °F) to 40 °C (104 °F)
  • pH Stability
    Working range 2–13, cleaning in place 1–14

Physicochemical Information

  • Bed Volume
    4000 mL
  • Ligand
    QA (strong anion exchanger, quaternary amine)

Product Information

  • Brand
    CIMmultus®
  • Package Type
    Individually Packed

Volume

  • Volume
    4000 mL