CIMac™ QA 0.1 mL Analytical Column (6 µm)

CIMac™ Analytical Columns are intended for fast and reproducible HPLC monitoring and quantitation of large proteins, plasmid DNA, viruses, virus-like particles, and phages. They were primarily designed for the in-process and final control of various samples at different stages of the purification process. They can be operated at high volumetric flow rates (from 1 to 20 column volumes/min); therefore, the information about the product quantity and purity can be obtained within a few minutes. CIMac™ Analytical Columns are fast and reliable PAT tools, providing:

• Rapid, high resolution analysis, achieved in minutes
• Flow independent separation
• High sensitivity and reproducibility

QA (quaternary amine) features:

• Strong anion exchanger
• Working range, pH 2–13
• Binds molecules with predominantly negative charge, repels molecules with a predominantly positive charge
• Use for capture, intermediate, or polishing steps in either bind-elute or flow-through mode
• High capacity for virus particles, IgM, exosomes
• High efficiency removal of endotoxin and DNA removal
• Outstanding for preparative applications or analytical finger-printing of process samples
• Sanitizable with 1 M NaOH