CIMac™ QA HR 0.1 mL Analytical Column (2 µm)

CIMac™ Analytical Columns are intended for fast and reproducible HPLC monitoring and quantitation of large proteins, plasmid DNA, viruses, virus-like particles, and phages. They were primarily designed for the in-process and final control of various samples at different stages of the purification process. They can be operated at high volumetric flow rates (from 1 to 20 column volumes/min); therefore, the information about the product quantity and purity can be obtained within a few minutes. CIMac™ Analytical Columns are fast and reliable PAT tools, providing:

• Rapid, high resolution analysis, achieved in minutes
• Flow independent separation
• High sensitivity and reproducibility

CIMac™ QA HR Analytical Columns are designed for fast and reproducible HPLC monitoring and quantification of empty or full capsids of different viruses. High reproducibility allows consistent separation of empty capsids, partially full capsids, aggregated & damaged capsids from full genome-containing viral capsids. With CIMac™ QAHR, even step elution analysis ensures reproducible separation of different viral capsids.

QA (quaternary amine) features:

• Strong anion exchanger
• HR stands for High Reproducibility
• For the highest AAV Empty-Full Reproducibility in AAV Analytics, even with step elution analysis
• Allows a maximum deviation of only up to ±3% of the concentration of the eluent salt at empty capsid elution