Celsius® FT100

Tech Support Documents
Celsius® FT100 Celsius® FT100 Celsius® FT100 Celsius® FT100
 

Celsius® FT100 is a controlled-rate freeze & thaw system designed to minimize the adverse effects of the cryoconcentration in your biopharmaceutical products. This modular equipment provides flexibility for processing up to 100L of solution with single-use Celsius® Paks.

Item No.: 
Celsius_FT100
Availability: 
Piece
1

*Custom/bulk order quotes are provided within 72 hours of request.

The Celsius® FT100 is a controlled-rate freeze and thaw system designed for freezing and thawing 1L, 2L, 8.3L and 16.6L Celsius® Paks.

The system is equipped with:

Three Cryo Chambers

The Heat Transfer Fluid (HTF) circulates inside heat transfer plates that are mounted on each chamber. Once a freeze or thaw cycle is initiated, the Celsius® FT100 ensures excellent contact between the plates and the Celsius® Pak surface to optimize the heat transfer. The Celsius® FT100 is mounted on rockers that allow the chamber to rock back and forward during thawing processes. This rocking movement optimizes the mixing of the liquid and solid phases of the product, improving thawing time and ensuring product homogeneity.

Conceived to minimize operator efforts, each chamber has a docking locator to align the Transfer Cart or the Celsius® SSM in order to simplify the transfer of the Celsius® Paks to and from each chamber.

Temperature Control Unit

The Temperature Control Unit (TCU) allows robust and reproducible freeze and thaw cycles. The TCU controls the freeze and thaw processes by supervising the temperature and flow rate of the heat transfer fluid according to predefined recipes.

Control Cabinet

The entire automatic freeze, thaw and hold operations are processed through the control cabinet. It is linked to the TCU and the freeze and thaw chambers via Profinet. The critical parameters of all processes are commanded, monitored and stored in an automatic manner with minimal operator intervention. The Human Machine Interface (HMI) is a touch screen panel PC connected to a Siemens PLC. All relevant process values are recorded with the WINCC software.

Applications

  • Application Area
    Frozen storage & shipping
  • Process Step
    • Bulk drug substance freezing and thawing
    • Process intermediates freezing and thawing

Dimensions

  • Dimensions WxDxH
    7000 x 1718 x 1835 mm

Features

  • Load Capacity
    • 6 × 16,6 L Celsius® Pak
    • 12 × 8,3 L Celsius® Pak
    • 24 × 2 L Celsius® Pak
    • 48 × 1 L Celsius® Pak

General Specifications

  • Additional Product Specifications
    Control unit: Siemens PLC
  • Temperature Range
    -60 °C - + 35 °C

Materials of Construction

  • Materials of Construction
    Stainless steel 1.4301 surface grinded

Power Requirements

  • Power Requirements
    FT module: 400 Volts, 3~N, 50 Hz or 480 Volts, 3~N, 60 Hz, Temperature Control Unit: 400 Volts, 3~N, 50 Hz or 460 Volts, 3~N, 60 Hz, Control Cabinet: 400 Volts, 3~N, 50 Hz or 480 Volts, 3~N, 60 Hz

Product Information

  • Brand
    Celsius® CFT
  • Freezer Technology
    Vertical plate freezing

Volume

  • Working Volume
    1 L - 100 L
  • Celsius® Pak Frame
    Celsius® Pak Frame
    Item no.
    Celsius-Pak-Frame

    Celsius® CFT Logistic Accessories are designed to minimize the manual handling of Celsius® Pak and to mitigate associated risks. This gives end-users the possibility to build an industrial process from filling and freezing to shipping, thawing, and dispensing.

  • SSM Trolley
    SSM Trolley
    Item no.
    FTH-SM00101-0020

    The SSM Trolley is designed to facilitate the transport of the Celsius® SSM (Shippable Storage Module) within a facility. It enables the reliable and secure movement of the SSM from the Celsius® CFT system to compatible freezers or shippers.

  • Celsius® Pak Single-Unit Shipper
    Celsius® Pak Single-Unit Shipper
    Item no.
    FTH-SM00102-0002

    The Celsius® Pak Single-unit Shipper is a robust, pre-qualified shipper that ensures the reliable transportation of individual frozen 8.3L or 16.6L Celsius® Paks. The Celsius® Pak Single-unit Shipper is refrigerated by dry-ice pellets and helps simplify the biopharmaceuticals supply chain

  • Celsius® CFT Transfer Carts
    Celsius® CFT Transfer Carts
    Item no.
    Celsius-CFT-Transfer-Carts

    The Celsius® Transfer Carts is designed to minimize the operator efforts when transferring Celsius® Pak into the Freeze-Thaw Modules. The Transfer Carts are available in two sizes: TC33 with a maximum carrying capacity of 33 L and TC100 with a maximum carrying capacity of 100 L

  • Adaptor, Freezer Storage
    Adaptor, Freezer Storage
    Item no.
    FTH-SR00080-0003

    Celsius® CFT Logistic Accessories are designed to minimize the manual handling of Celsius® Pak and to mitigate associated risks. This gives end-users the possibility to build an industrial process from filling and freezing to shipping, thawing, and dispensing.

  • Celsius® Pak frame 2G RTD Holder
    Celsius® Pak frame 2G RTD Holder
    Item no.
    FTH-CF00000-0029

    The Celsius® Pak Frame RTD Holder allows for proper placement of the temperature probe inside the thermowell of the 8.3L and 16.6L Celsius® Paks. This enables non-invasive temperature monitoring of the last point to freeze in the Paks.

  • Celsius® Shippable Storage Module (SSM)
    Celsius® Shippable Storage Module (SSM)
    Item no.
    FTH-SM00101-0024

    The Celsius® Shippable Storage Module (SSM) allows for storage of up to 100L of frozen product in 1L, 2L, 8.3L and 16.6L Celsius® Paks. The Celsius® SSM can be directly placed inside the Celsius® SSM Shipper for reliable frozen transport to remote locations.

  • SSM Insulated Cover
    SSM Insulated Cover
    Item no.
    FTH-SM00101-0027

    Celsius® CFT Logistic Accessories are designed to minimize the manual handling of Celsius® Pak and to mitigate associated risks. This gives end-users the possibility to build an industrial process from filling and freezing to shipping, thawing, and dispensing.

  • SM100 Trolley
    SM100 Trolley
    Item no.
    FTH-SM00101-0010

    Celsius® CFT Logistic Accessories are designed to minimize the manual handling of Celsius® Pak and to mitigate associated risks. This gives end-users the possibility to build an industrial process from filling and freezing to shipping, thawing, and dispensing.

  • SM100 – Storage Module
    SM100 – Storage Module
    Item no.
    FTH-SM00100-0070

    Celsius® CFT Logistic Accessories are designed to minimize the manual handling of Celsius® Pak and to mitigate associated risks. This gives end-users the possibility to build an industrial process from filling and freezing to shipping, thawing, and dispensing.

  • Celsius® Pak Carrier, 1 L and 2 L
    Celsius® Pak Carrier, 1 L and 2 L
    Item no.
    FTH-CF00004-0020

    The Celsius® Pak Carrier allows for the processing of the 1L or 2L Celsius® Paks in the Celsius® FT100. The Celsius® Pak Carrier can receive up to eight 1L Celsius® Paks, four 2L Celsius® Paks, or a mix of each.

  • Celsius® SSM shipper
    Celsius® SSM shipper
    Item no.
    FTH-SM00101-0028

    The Celsius® SSM Shipper is a robust, pre-qualified, reusable shipping solution that ensures the reliable transportation of frozen 8.3L and 16.6L Celsius® Paks stored in Celsius® SSMs to remote locations. Refrigerated by dry-ice slabs, the shipper can transport up to 100L of product per unit.

  • Celsius® Pak
    Celsius® Pak
    Item no.
    M_Celsius_Pak

    Celsius® CFT is an industry-leading platform technology that controls freezing and thawing rates to minimize cryo-concentration in biopharmaceutical products.

    This platform ensures substances are well-protected and offers flexibility by processing up to 100L in single-use Celsius® Paks.