Sartobind® Rapid A 0.8 L Cassette

Tech Support Documents
Sartobind® Rapid A 0.8 L Cassette Sartobind® Rapid A 0.8 L Cassette
 

Sartobind® 0.8 L cassettes are used in the Pilot Scale Filter Holder of up to 10.4 L membrane volume for the biopharmaceutical production. They must be used in an appropriate cassette holder and one Manifold Set.

Item No.: 
98R-PA19D-L

*Custom/bulk order quotes are provided within 72 hours of request.

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Sartobind® Rapid A is a membrane chromatography platform designed for modern monoclonal antibody purification processes, offering a scalable solution for capturing Fc-region containing biomolecules, ideal for process intensification in single- or multi-column setups.

  • Ready-for-use consumables, quick and easy setup
  • Scalable, cost-efficient portfolio
  • Enables process intensification, shorter timelines
  • Membrane designed for shorter residence time and diverse mAb sizes
  • Designed for full utilization of the membrane’s lifespan
  • Expert, tailored consultancy services

With its high binding capacity, short residence times, and low operating pressures, Sartobind® Rapid A offers seamless scalability from process development to commercial production.

Applications

  • Application
    Capture

Compliance Information

  • Biological Reactivity
    • The final product meets the requirements of the current ISO 10993-5 which is equivalent to the current United States Pharmacopoeia (USP) <87> Biological Reactivity Tests, in vitro.
    • All in-contact plastic components meet the requirements of current USP <88> Biological Reactivity Tests, in vivo, for Plastic Class VI (Systemic Injection, Intracutaneous and Implantation Tests).

Connections (Physical)

  • Connectors
    Sanitary 1" – 1.5"

Dimensions

  • Bed Height
    4 mm
  • Dimensions
    634 × 49 × 387 mm

Materials of Construction

  • Housing Material
    Acrylonitrile butadiene styrene (ABS)

Operating Conditions

  • Maximum Operating Pressure
    0.2 MPa
  • Maximum Venting Pressure
    0.5 bar, 0.05 MPa, 7 psi
  • Recommended Flow Rate
    3-5 MV/min (load, elution), 5-10 MV/min ( equilibration, wash)
  • pH Stability
    pH 2 – 14 (short term), pH 3 – 13 (long term)

Physicochemical Information

  • Bed Volume
    0.8 L
  • Chemical Compatibility
    Stable in common chromatography buffers, unstable to peroxide and other oxidizing or reactive reagents
  • Ligand
    Protein A
  • Reference Protein
    Human polyclonal IgG
  • Typical Dynamic Binding Capacity 10% per mL
    ≥ 30 mg/mL
  • Void Volume
    2500 mL

Product Information

  • Brand
    Sartobind® Rapid A
  • Membrane Adsorber Format
    Cassettes
  • Membrane Type
    Affinity
  • Pack Size
    1
  • What you receive
    • 1 cassette
    • 1 operating instruction
    • 1 certificate
  • Manifold Set for Sartoclear® Depth Filters and Sartobind® Membrane Adsorbers
    Manifold Set for Sartoclear® Depth Filters and Sartobind® Membrane Adsorbers
    Item no.
    29Z-S00001

    The manifold set contains the inlet and outlet adapter plates for Sartoclear® Depth Filters as well as Sartobind® membrane adsorbers cassettes.

  • Process Filter Holder — For Sartoclear® Depth Filters and Sartobind® Membrane Adsorbers
    Process Filter Holder — For Sartoclear® Depth Filters and Sartobind® Membrane Adsorbers
    Item no.
    2ZGL--0006

    Filter Holders are hydraulic clamping systems especially designed for the use of modular Sartoclear® Depth Filter cassettes and Sartobind® membrane chromatography cassettes. The holders are available in three standard formats for pilot scale and commercial manufacturing.

  • Double Process Filter Holder — For Sartoclear® Depth Filters and Sartobind® Membrane Adsorbers
    Double Process Filter Holder — For Sartoclear® Depth Filters and Sartobind® Membrane Adsorbers
    Item no.
    2ZGL--0007

    Filter Holders are hydraulic clamping systems especially designed for the use of modular Sartoclear® Depth Filter cassettes and Sartobind® membrane chromatography cassettes. The holders are available in three standard formats for pilot scale and commercial manufacturing.

  • Pilot Filter Holder — For Sartoclear® Depth Filters and Sartobind® Membrane Adsorbers
    Pilot Filter Holder — For Sartoclear® Depth Filters and Sartobind® Membrane Adsorbers
    Item no.
    2ZGL--0005

    Filter Holders are hydraulic clamping systems especially designed for the use of modular Sartoclear® Depth Filter cassettes and Sartobind® membrane chromatography cassettes. The holders are available in three standard formats for pilot scale and commercial manufacturing.