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Sartoflow® Expert SU

Tech Support Documents
Sartoflow® Expert SU Sartoflow® Expert SU Sartoflow® Expert SU Sartoflow® Expert SU Sartoflow® Expert SU Sartoflow® Expert SU Sartoflow® Expert SU
 

Efficient and Versatile - The TFF System from PD to Pilot

One-skid solution is safe and efficient

A single system streamlines three steps (mixing, filtration, UF/DF) and eliminates product transfer.

Fully scalable single-use solution

Versatile cGMP single-use TFF system provides a seamless transition from 1-20 L scale (i.e. 2 - 100 L starting volume).

Flexible process sequencing

The system has the flexibility to accommodate different sequences of process steps.

Reduced bioburden, ready-to-use system

A gamma-irradiated closed-loop system prevents leaks and eliminates cleaning and validation efforts.

Item No.: 
SFEXPERTSU
*Custom/bulk order quotes are provided within 72 hours of request.
Sartoflow® Expert SU
Sartoflow® Expert SU

Efficient and Versatile - The TFF System from PD to Pilot

One-skid solution is safe and efficient

A single system streamlines three steps (mixing, filtration, UF/DF) and eliminates product transfer.

Fully scalable single-use solution

Versatile cGMP single-use TFF system provides a seamless transition from 1-20 L scale (i.e. 2 - 100 L starting volume).

Flexible process sequencing

The system has the flexibility to accommodate different sequences of process steps.

Reduced bioburden, ready-to-use system

A gamma-irradiated closed-loop system prevents leaks and eliminates cleaning and validation efforts.

Item No.:
SFEXPERTSU

Overview

Specifications

Choose your Tangential Flow Filtration (TFF) Systems

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3-In-1 Single Use Approach

The Sartoflow® Expert SU is a flexible fully automated single-use TFF system for process development and pilot-scale manufacturing in accordance with GMP regulations, running filtration sizes from 0.14 up to 1.4 m² in 1 - 20 L scale.

It streamlines up to three process steps - mixing, sterile-grade filtration and ultrafiltration/diafiltration in a robust fully single-use closed loop, to ensure operator safety, product integrity and process quality.

The Sartoflow® Expert SU features an intuitive visual and software-based guidance to ensure the correct installation of the single-use components. Several peristaltic pumps are available for automated transfer and addition of process fluids.

Transform Your Bioprocessing Efficiency with the Sartoflow® Expert SU System

Features & Benefits of the Sartoflow® Expert SU System

  • Automated workflow
  • Closed-loop design
  • Multi-process capability
  • Broad application spectrum
  • Single-use design
  • Multiple unit operations in one system
  • Enhanced process controls
  • Batch size adaptability
  • Gamma-irradiated flow kits
  • Intuitive interface

Consumables for the Sartoflow® Expert SU

The Sartoflow® Expert SU is compatible with the following TFF cassettes:

  • Sartocon® Slice Self-Contained ECO
  • Sartocube® Self-Contained ECO

The Sartoflow® Expert SU is compatible with the following flow kit:

  • Sartoflow® Expert SU Permeate and Retentate Flow Kit (SFE-TUB-PERM-RET)
  • Sartoflow® Expert SU Feed Flow Kit (SFE-TUB-FEED)
  • Sartoflow® Expert SU Prefiltration Flow Kit (SFE-TUB-PRECIFIL)
  • Sartoflow® Expert SU Media Addition Flow Kit (SFE-TUB-MANIFOLD)
  • Mycap® Single-Use Cap (MYCAPSSBL0001)

The Sartoflow® Expert SU is compatible with the following bag:

  • Recirculation - 20 L 3D mixing bag with sampling port, conductivity probe (FMS310600)
  • 2nd Mixing Bag (only for configured system) - 20 L 3D mixing bag with sampling port, pH probe (FMS310569)

Applications

  • Application
    • Purification of mAbs, ADC, vaccines, viral vectors, and recombinant proteins
    • Concentration
    • Microfiltration
    • Ultrafiltration
    • Desalting
    • Buffer Exchange
    • Single Use Processing
    • Antibody Purification
    • Protein Concentration
    • DNA Concentration
    • mRNA concentration
    • Conjugation
    • ADC

Connections (Physical)

  • Connector(s)
    • MPC
    • AseptiQuik® Connector
    • Luer connectors

Dimensions

  • Dimensions WxDxH
    Base Unit: 1,430 x 755 x 1,755 mm (nominal) With 2nd bag holder: 1,875 x 755 x 1,755 mm (nominal)
  • Membrane Area
    0.14, 0.28, 0.42, 1.4 m²
  • Tube Size (ID – OD)
    3/8"

Features

  • Display
    Colored Touchscreen
  • Display Size
    22"
  • Sensors
    • pH
    • Conductivity
    • Pressure
    • Flow
    • Temperature
    • UV
  • Temperature Control
    Refrigerated and heated
  • Temperature Sensor
    pT100

General Specifications

  • Cassette Format
    • Sartocon® SCU
    • Sartocube® SCU
    • Sartocon Cassettes
    • Sartocube Cassettes
  • Filter Format
    Cassettes
  • Pump Output
    Up to 900 L/h

Materials of Construction

  • Materials of Construction
    Stainless steel
  • Recirculation Vessel
    single-use
  • Tubing Material
    • Silicone
    • TPE

Operating Conditions

  • Maximum Operating Pressure
    4 bar | 58 psi
  • Minimum Operating Volume
    ~ 600 mL
  • Recommended Operating Temperature
    10 to 40 C°

Power Requirements

  • Power Requirements
    100 - 120 V, 50/60 Hz, 9A220 - 240 V, 50/60 Hz, 5A

Product Information

  • Brand
    • Ambr® crossflow
    • Sartoflow®

Volume

  • Bag Volume
    1-20 L (20 L 3D mixing bag)
  • Hold-up Volume
    ~ 400 mL
  • Recirculation Vessel Volume
    1-20 L (20 L 3D mixing bag)

Weight

  • Total Weight
    450 kg