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Chromatography (791)
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The mFix4 mRNA standard is a 3969 nt long mRNA molecule with a poly-adenylated tail of 95 nt. The molecule is produced by IVT reaction with a DNA template retrieved from recombinant microbial expression (E. coli). Its primary use is System Suitability Testing.
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The PATfix® AAV Switcher Platform is a chromatography-based analytical platform that simplifies AAV quality monitoring with a 2-step process – capture and separation – to accurately measure viral quality from the complex upstream samples.
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PATfix® LNP Switcher is a chromatography-based analytical platform tailored for lipid nanoparticle (LNP) characterization, enabling at-line determination of encapsulation efficiency, particle size, and lipid composition to accelerate nucleic acid–based therapeutic development.
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Plasmid pFix15 standard is a 15.4 kb plasmid DNA isolated from E. coli and chromatographically purified. It is mainly intended for System Suitability Testing and preparation of a standard curve.
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0,1 mL
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Analytical Columns
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PrimaS (multimodal - anion exchange-hydrogen bonding)
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CIMac™
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Oligo dT18 coupled to CDI-activated matrix, C12 Linker
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CIM®
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Screening, Gene therapy
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2μm
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SDVB (reverse phase, poly(styrene-co-divinylbenzene))
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CIM®
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Screening, Gene therapy
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2μm
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Oligo dT18 coupled to CDI-activated matrix, C6 Linker
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CIM®
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Screening, Gene therapy
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2μm
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PrimaS (multimodal - anion exchange-hydrogen bonding)
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CIM®
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Screening, Gene therapy
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2μm
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SO3 (strong cation exchanger, sulfonate)
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CIM®
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Screening, Gene therapy
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2μm
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C4 HLD (hydrophobic, butyl – high ligand density)
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CIM®
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Screening, Gene therapy
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2μm
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QA HR (strong anion exchanger, quaternary amine)
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CIM®
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Screening, Gene therapy
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2μm
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Swiper (multimodal - anion exchange-hydrogen bonding)
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CIM®
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Screening, Gene therapy
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2μm
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PrimaT (multimodal - anion exchange-hydrogen bonding-metal affinity)
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CIM®
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Screening, Gene therapy
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2μm
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0.08 mL
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Capturing, Polishing
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Quaternary ammonium, Sulfonic acid, Primary amine (PA)
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4 mm
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