CIMac™ Adeno 0.1 mL Analytical Column (2 µm)
CIMac™ Adeno Analytical Columns are intended for fast and reproducible analysis and quantification of Adenovirus samples at different stages of downstream and upstream.
- Item No.:
- 110.8502-2
- Piece
- 1
*Custom/bulk order quotes are provided within 72 hours of request.
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The CIMac™ Adeno-0.1 Analytical Columns are intended for fast and reproducible HPLC monitoring and quantitation of any type of Adenovirus. They were primarily designed for the in-process and final control of Adenovirus samples at different stages of the purification process. They can be operated at high volumetric flow rates (from 1 to 20 column volumes/min); therefore, the information about the Adenovirus quantity and purity can be obtained within a few minutes. CIMac™ Adeno-0.1 Analytical Columns are fast and reliable PAT tools, providing:
- Rapid, high resolution analysis, achieved in minutes
- Flow independent separation
- High sensitivity and reproducibility
Adeno features:
- Strong anion exchanger
- Enables fast and reproducible HPLC monitoring and quantitation of any type of Adenovirus
Applications
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ApplicationAnalytical Columns
Connections (Physical)
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Connector(s)10-32 UNF coned port, 0.0625" OD tubing connection
Dimensions
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Channel Size2 µm
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Diameter5.2 mm
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Length4.95 mm
Features
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ReusableYes
General Specifications
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Flow Rate0.2 – 3 mL/min | 1 – 15 cm/min | 2 – 30 CV/min
Materials of Construction
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Materials of ConstructionPoly(glycidyl methacrylate -co- ethylene dimethacrylate)
Operating Conditions
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Maximum Operating Pressure15 MPa | 150 bar | 2175 psi
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Recommended Operating Temperature4 °C (39 °F) to 40 °C (104 °F)
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pH StabilityWorking range 2–13, cleaning in place 1–14
Physicochemical Information
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Bed Volume0.1 mL
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LigandQA modified for Adeno (strong anion exchanger, quaternary amine)
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Typical Dynamic Binding Capacity 10% per mL25–31 mg BSA/mL wet support, BSA, 0.5 mg/mL, 20 mM Tris-HCI buffer, pH 7.4, flowrate 1 mL/min
Product Information
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BrandCIMac™
Biocompatible analytical chromatography system with quaternary buffer setup.
PATfix® analytical quaternary system is an at-line tool, to help process developers of novel gene therapies get immediate feedback on their current process state. This enables faster iteration and process optimization towards better purities and higher recoveries. The Sartorius analytical system provides modality-appropriate analysis and in-process control for gene therapy and vaccine products. Designed to take full advantage of the capabilities of CIMac™ analytical monolithic columns, the PATfix® delivers fast, high-resolution runs. Operation with multiple detector types provides content- rich analyses even with complex samples. User friendly PATfix® software makes for easy data processing, visualization and sharing.