CIMac™ Analytical Columns combine all elaborate characteristics of CIM^® monoliths at analytical scale and are your perfect tool for analysis and control of manufacturing processes, ideal for process analytical technology (PAT).

Designed for fast and reproducible HPLC monitoring and quantitation of proteins, viruses, pDNA, and other large biomolecules, they allow you to achieve rapid, high-resolution and flow-independent separations in a matter of minutes.

Availability:

*Custom/bulk order quotes are provided within 72 hours of request.

Products (26)

CIMac™ pDNA 0.3 mL Analytical Column (6 µm)
Ligand:

DEAE (weak anion exchanger, diethylamino)
Bed Volume:

0.3 mL
Channel Size:

6 µm
Item no.

150.8501-6

Item no.

150.8501-6
CIMac™ QA HR 0.1 mL Analytical Column (2 µm)
Ligand:

QA HR (strong anion exchanger, quaternary amine)
Bed Volume:

0,1 mL
Channel Size:

2 µm
Item no.

BIA-110.5213-2

Item no.

BIA-110.5213-2
CIMac™ QA 0.1 mL Analytical Column (1.3 µm)

Documents
Ligand:

QA (strong anion exchanger, quaternary amine)
Bed Volume:

0.1 mL
Channel Size:

1.3 µm
Item no.

110.5113-1.3

Item no.

110.5113-1.3
CIMac™ AAV full/empty 0.1 mL Analytical Column (1.3 µm)
Ligand:

QA modified for AAV (strong anion exchanger, quaternary amine)
Bed Volume:

0.1 mL
Channel Size:

1.3 µm
Item no.

110.8503-1.3

Item no.

110.8503-1.3
CIMac™ EDA 0.1 mL Analytical Column (1.3 µm)

Documents
Ligand:

EDA (weak anion exchanger, ethylene diamine)
Bed Volume:

0.1 mL
Channel Size:

1.3 µm
Item no.

110.5116-1.3

Item no.

110.5116-1.3
CIMac™ QA 0.1 mL Analytical Column (6 µm)

Documents
Ligand:

QA (strong anion exchanger, quaternary amine)
Bed Volume:

0.1 mL
Channel Size:

6 µm
Item no.

110.5113-6

Item no.

110.5113-6
CIMac™ pDNA 0.3mL Analytical Column (1.4 µm)
Ligand:

DEAE (weak anion exchanger, diethylamino)
Bed Volume:

0.3 mL
Channel Size:

1.4 µm
Item no.

150.8501-1.4

Item no.

150.8501-1.4
CIMac™ SO3 0.1 mL Analytical Column (1.3 µm)

Documents
Ligand:

SO3 (strong cation exchanger, sulfonate)
Bed Volume:

0.1 mL
Channel Size:

1.3 µm
Item no.

110.6157-1.3

Item no.

110.6157-1.3
CIMac™ Adeno 0.1 mL Analytical Column (2 µm)
Ligand:

QA modified for Adeno (strong anion exchanger, quaternary amine)
Bed Volume:

0.1 mL
Channel Size:

2 µm
Item no.

110.8502-2

Item no.

110.8502-2
CIMac™ EDA 0.1 mL Analytical Column (2 µm)

Documents
Ligand:

EDA (weak anion exchanger, ethylene diamine)
Bed Volume:

0.1 mL
Channel Size:

2 µm
Item no.

110.5116-2

Item no.

110.5116-2
CIMac™ DEAE 0.1 mL Analytical Column (1.3 µm)

Documents
Ligand:

DEAE (weak anion exchanger, diethylamino)
Bed Volume:

0.1 mL
Channel Size:

1.3 µm
Item no.

110.5114-1.3

Item no.

110.5114-1.3
CIMac™ r-Protein A 0.1 mL Analytical Column (2 µm)

Documents
Ligand:

r-Protein A (affinity, recombinant protein A produced from E. Coli coupled to CDI-preactivated support)
Bed Volume:

0.1 mL
Channel Size:

2 µm
Item no.

110.1004-2

Item no.

110.1004-2
CIMac PrimaS® 0.1 mL Analytical Column (2 µm)

Documents
Ligand:

Multimodal (anion exchange-hydrogen bonding)
Bed Volume:

0,1 mL
Channel Size:

2 µm
Item no.

110.5118-2

Item no.

110.5118-2
CIMac™ OH 0.1 mL Analytical Column (1.3 µm)
Ligand:

OH (hydrophobic, hydroxyl)
Bed Volume:

0,1 mL
Channel Size:

1.3 µm
Item no.

110.8140-1.3

Item no.

110.8140-1.3
CIMac™ Oligo dT18 0.1 mL Analytical Column (C6 Linker) (2 µm)

Documents
Ligand:

Oligo dT18 coupled to CDI-activated matrix, C6 Linker
Bed Volume:

0.1 mL
Channel Size:

2 µm
Item no.

110.1218-2

Item no.

110.1218-2

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Overview

CIMac™ Analytical Columns are short-bed high-performance monolithic columns offering all the advantages of CIM^® monolithic technology. Their small volume and short length enable high volumetric flow rates, allowing for the rapid acquisition of quantity and purity information within minutes.

Hence, the CIMac™ Analytical Columns are ideal for the in-process and final control of various samples from different purification process steps.

Features:

Volume of 0.1 mL (0.3 mL for CIMac™ pDNA)
Flow rates from 1 to 30 column volumes/minute (varies by type)
Application-optimized channel widths
Available in a wide variety of chemistries

Benefits:

Analytical HPLC columns for nucleic acids, viral vectors, viruses, and other biomolecules
In-process analysis and quantitation, and final product
At-line monitoring and control of manufacturing processes (PAT)
Rapid, high-resolution analysis achieved in minutes
High sensitivity, accuracy and reproducibility
No sample carryover

Documents

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