CIMac™ CDI 0.1 mL Analytical Column (1.3 µm)
Carboxyimidazole (CDI) monolithic chromatographic columns are used for covalent immobilisation of ligands (e.g. proteins, peptides and other amine- or thiol-containing molecules).
- Item No.:
- 110.8000-1.3
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CIMac™ Analytical Columns are short-bed high-performance monolithic columns offering all the advantages of CIM® monolithic technology. Their small volume and short column length allow the operation at high volumetric flow rates, enabling them to receive the information about the product quantity and purity in just a few minutes. Hence, the CIMac™ Analytical Columns can be effectively used for the in-process and final control of various samples from different purification process steps.
CIMac™ CDI Analytical Columns columns are used for covalent immobilisation of ligands (e.g. proteins, peptides and other amine- or thiol-containing molecules). The covalent nature of the bond between the ligand and matrix reduces leaching and improves stability and reusability. Immobilised supports enable a variety of customised analytical affinity chromatography options with interactions specific to the target molecule.
CDI (carboxy imidazole) features:
- Forms a covalent carbamate linkage with amino and thiol-containing molecules
- Suitable for coupling of sensitive molecules, such as peptides, proteins, oligonucleotides
Applications
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ApplicationAnalytical Columns
Connections (Physical)
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Connector(s)10-32 UNF coned port, 0.0625" OD tubing connection
Dimensions
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Channel Size1.3 µm
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Diameter5.2 mm
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Length4.95 mm
Features
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ReusableYes
General Specifications
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Flow Rate0.2 – 3 mL/min | 1 – 15 cm/min | 2 – 30 CV/min
Materials of Construction
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Materials of ConstructionPoly(glycidyl methacrylate -co- ethylene dimethacrylate)
Operating Conditions
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Maximum Operating Pressure15 MPa | 150 bar | 2175 psi
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Recommended Operating Temperature2 °C (36 °F) to 8 °C (46 °F)
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pH StabilityWorking range 3–13, cleaning in place 1–14
Physicochemical Information
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Bed Volume0,1 mL
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LigandCDI (activated; carboxy imidazole)
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Ligand Density0.15–0.3 mmol/mL wet support
Product Information
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BrandCIMac™
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