CIMac™ SDVB 0.1 mL Analytical Column (2 µm)
Strongly hydrophobic styrene divinylbenzene is a versatile reversed phase chromatography ligand enabling high throughput and high-resolution analytics.
- Item No.:
- BIA-110.9001-2
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CIMac™ Analytical Columns are short-bed high-performance monolithic columns offering all the advantages of CIM® monolithic technology. Their small volume and short column length allow the operation at high volumetric flow rates, enabling them to receive the information about the product quantity and purity in just a few minutes. Hence, the CIMac™ Analytical Columns can be effectively used for the in-process and final control of various samples from different purification process steps.
Strongly hydrophobic styrene divinylbenzene (SDVB) is a versatile reversed phase chromatography ligand enabling high throughput and high-resolution analytics. It is suited for different applications:
- Characterisation of non-single-strand RNA in mRNA material
- Separation of complex protein mixtures coupled with LC-MS analysis
- Analysis of natural polymers (oligonucleotides, DNA, RNA)
- Analysis of synthetic polymersAvailable as CIMmultus preparative column for purification
Applications
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ApplicationAnalytical Columns
Connections (Physical)
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Connector(s)10-32 UNF coned port, 0.0625" OD tubing connection
Dimensions
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Channel Size2 µm
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Diameter5.2 mm
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Length4.95 mm
Features
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ReusableYes
General Specifications
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Flow Rate0.2 – 3 mL/min | 1 – 15 cm/min | 2 – 30 CV/min
Materials of Construction
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Materials of ConstructionPoly(styrene-co-divinylbenzene)
Operating Conditions
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Maximum Operating Pressure15 MPa | 150 bar | 2175 psi
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Recommended Operating Temperature2 °C (36 °F) to 25 °C (77 °F)
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pH StabilityWorking range 2–13, cleaning in place 1–14
Physicochemical Information
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Bed Volume0.1 mL
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LigandSDVB (reverse phase, poly(styrene-co-divinylbenzene))
Product Information
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BrandCIMac™
Biocompatible analytical chromatography system with quaternary buffer setup.
PATfix® analytical quaternary system is an at-line tool, to help process developers of novel gene therapies get immediate feedback on their current process state. This enables faster iteration and process optimization towards better purities and higher recoveries. The Sartorius analytical system provides modality-appropriate analysis and in-process control for gene therapy and vaccine products. Designed to take full advantage of the capabilities of CIMac™ analytical monolithic columns, the PATfix® delivers fast, high-resolution runs. Operation with multiple detector types provides content- rich analyses even with complex samples. User friendly PATfix® software makes for easy data processing, visualization and sharing.