CIMmultus^® is a unique and industry-proven line of pre-packed chromatographic monolithic columns featuring large flow-through channels, which make them ideal for purifying large biomolecules such as viruses (AAV, adenovirus, lentivirus, influenza, bacteriophages), nucleic acids (mRNA, pDNA), virus-like particles and exosomes.

Without the need for column packing, CIMmultus^® columns are ready for use out of the box.

Available in:

Varied monolith volumes
Wide range of CIM^® chemistries
Differing channel sizes

Availability:

*Custom/bulk order quotes are provided within 72 hours of request.

Products (258)

CIMmultus® CDI 800 mL Monolithic Column (2 μm)
Ligand:

CDI (activated; carboxy imidazole)
Bed Volume:

800 mL
Channel Size:

2 µm
GMP Compliance:

No
Item no.

811.8000-2

Item no.

811.8000-2
CIMmultus® OH 40 mL cGMP Compliant Monolithic Column (2 µm)
Ligand:

OH (hydrophobic, hydroxyl)
Bed Volume:

40 mL
Channel Size:

2 µm
Package Type:

Individually Packed
Item no.

914.8140-2

Item no.

914.8140-2
CIMmultus® CDI 40 mL Monolithic Column (2 μm)
Ligand:

CDI (activated; carboxy imidazole)
Bed Volume:

40 mL
Channel Size:

2 µm
GMP Compliance:

No
Item no.

BIA-614.8000-2

Item no.

BIA-614.8000-2
CIMmultus® Oligo dT18 (C6 Linker) 4 mL cGMP Compliant Monolithic Column (2 μm)
Ligand:

Oligo dT18 coupled to CDI-activated matrix, C6 Linker
Bed Volume:

4 mL
Channel Size:

2 µm
Package Type:

Individually Packed
Item no.

BIA-904.1218-2

Item no.

BIA-904.1218-2
CIMmultus® OH 4000 mL cGMP Compliant Monolithic Column (2 µm)
Ligand:

OH (hydrophobic, hydroxyl)
Bed Volume:

4000 mL
Channel Size:

2 µm
Package Type:

Individually Packed
Item no.

934.8140-2

Item no.

934.8140-2
CIMmultus® OH 800 mL Monolithic Column (2 µm)
Ligand:

OH (hydrophobic, hydroxyl)
Bed Volume:

800 mL
Channel Size:

2 µm
GMP Compliance:

No
Item no.

811.8140-2

Item no.

811.8140-2
CIMmultus® OH 400 mL cGMP Compliant Monolithic Column (2 µm)
Ligand:

OH (hydrophobic, hydroxyl)
Bed Volume:

400 mL
Channel Size:

2 µm
Package Type:

Individually Packed
Item no.

924.8140-2

Item no.

924.8140-2
CIMmultus® CDI 4000 mL Monolithic Column (2 μm)
Ligand:

CDI (activated; carboxy imidazole)
Bed Volume:

4000 mL
Channel Size:

2 µm
GMP Compliance:

No
Item no.

BIA-1014.8000-2

Item no.

BIA-1014.8000-2
CIMmultus® SO3 4 mL cGMP Compliant Monolithic Column (2 μm)
Ligand:

SO3 (strong cation exchanger, sulfonate)
Bed Volume:

4 mL
Channel Size:

2 µm
Package Type:

Individually Packed
Item no.

904.6157-2

Item no.

904.6157-2
CIMmultus® SO3 4000 mL cGMP Compliant Monolithic Column (6 μm)
Ligand:

SO3 (strong cation exchanger, sulfonate)
Bed Volume:

4000 mL
Channel Size:

6 µm
Package Type:

Individually Packed
Item no.

BIA-934.6157-6

Item no.

BIA-934.6157-6
CIMmultus® CDI 80 mL Monolithic Column (2 μm)
Ligand:

CDI (activated; carboxy imidazole)
Bed Volume:

80 mL
Channel Size:

2 µm
GMP Compliance:

No
Item no.

611.8000-2

Item no.

611.8000-2
CIMmultus® OH 4000 mL Monolithic Column (6 µm)
Ligand:

OH (hydrophobic, hydroxyl)
Bed Volume:

4000 mL
Channel Size:

6 µm
GMP Compliance:

No
Item no.

BIA-1014.8140-6

Item no.

BIA-1014.8140-6
CIMmultus® SDVB 4000 mL Monolithic Column (2 μm)
Ligand:

SDVB (reverse phase, poly(styrene-co-divinylbenzene))
Bed Volume:

4000 mL
Channel Size:

2 µm
GMP Compliance:

No
Item no.

1014.9001-2

Item no.

1014.9001-2
CIMmultus PrimaS® 4000 mL Monolithic Column (2 μm)
Ligand:

Multimodal (anion exchange-hydrogen bonding)
Bed Volume:

4000 mL
Channel Size:

2 µm
GMP Compliance:

No
Item no.

BIA-1014.5118-2

Item no.

BIA-1014.5118-2
CIMmultus PrimaS® 800 mL Monolithic Column (2 μm)
Ligand:

Multimodal (anion exchange-hydrogen bonding)
Bed Volume:

800 mL
Channel Size:

2 µm
GMP Compliance:

No
Item no.

811.5118-2

Item no.

811.5118-2

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Overview

CIMmultus^® Monoliths are reusable chromatography devices for scalable high-resolution purification of complex biological samples. Inside the custom-designed housing is a single-piece stationary phase with homogeneous channel size and surface chemistry. This stationary phase is designed to simplify method transfer from development into production.

Features

Available with a wide range of chemistries
Various channel size options
Scalable from 1 mL to 40 L
Single batch use or multiuse
cGMP compliant

Benefits

Very fast processes by convective mass transport – resolution independent of flow
Ready to use columns
High-capacity for large molecules due to fully accessible void volume in the channels
Laminar flow minimizes shear stress resulting in high yields

Specifications

Product Information

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CIMmultus®

CIMmultus®

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