Incucyte® 3D Nanowell 96-well Microplate for Organoid Assays - 500 µm

The Incucyte^® 3D Nanowell Plates facilitate high-throughput organoid studies by creating a 3D microenvironment that mimics in vivo conditions, supporting organoid growth and differentiation. These plates feature an array of hydrogel-printed microwells, each optimized to foster uniform and reproducible organoid formation. Additionally, each well contains a dedicated pipetting port for seamless medium changes that can be integrated with automated processes, thus enhancing efficiency and reproducibility in large-scale screening assays. Together with the Incucyte^® Live-Cell Analysis System and Incucyte^® Organoid Analysis Software Module (9600-0034), these plates enable high-throughput, long-term imaging and analysis of organoids, providing insights into their growth and viability dynamics. This plate also requires systems to be operating on Incucyte^® Base Software v2024A or later.

Incucyte^® 3D Nanowell Plates are designed for consistent and reproducible results across experiments, ensuring uniformity in cell culture conditions, minimizing variability and enhancing the reliability of experimental outcomes. Each well of the Incucyte^® 3D Nanowell Plate contains an array of 73 microwells (500 µm diameter) for homogeneous organoid formation and high-throughput label-free evaluation of organoids all within a single plate.

Unlike conventional 2D cell culture, Incucyte^® 3D Nanowell Plates provide a biomimetic environment to better mimic in vivo conditions, offering researchers deeper insights into cell interactions, morphology, and function. This enhanced physiological relevance is crucial for applications such as cancer research, regenerative medicine, and drug development, where accurate modeling of tissue microenvironments is essential.

Incucyte^® 3D Nanowell Plates are ready-to-use and come with lab-tested protocols that improve efficiency in experimental set up, minimize Matrigel^® handling, and enable the long-term evaluation of organoids. Save time and resources and reduce potential variability introduced by manual Matrigel^® application, ensuring more consistent and reliable experimental results.

As opposed to other methods such as embedding organoids in Matrigel^®, the Incucyte^® 3D Nanowell Plates keep organoids within the same focal plane therefore reducing imaging artifacts. Incucyte^® 3D Nanowell Plates have been validated for use with Incucyte^® Live-Cell Analysis Systems with base software v2024A or later, and require the Incucyte^® Organoid Analysis Software Module to automatically locate, image, and analyzes organoids to providing powerful insight into morphology, size and count.

Each plate is individually packaged, sterile and TC-treated, and should be stored upright at 2-8^oC upon receipt.