Top Features for Recombinant Human Activin A:

  • Optimal use for differentiation of iPSCs and ESCs into definitive endoderm
  • ADCF Level 2
  • High purity to ensure the safety of your process
  • Available in two different grades (Preclinical and GMP grade)

Preclinical grade:

  • Intended for preclinical ex vivo use
  • GMP transferable: Seamless transition from preclinical development to commercial manufacturing

GMP grade:

  • Intended for clinical ex vivo use
  • Endotoxin Level ≤ 50 EU/mg
  • Manufactured in accordance with applicable GMP guidelines
  • Technical and regulatory support available

Item No.: 

*Custom/bulk order quotes are provided within 72 hours of request.

CellGenix® rh Cytokines - Preclinical vs GMP

Both product grades are produced under the same conditions in a GMP facility, ensuring an equal product quality and performance. We offer a more comprehensive QC testing including tighter specifications and documentation for our GMP products: CellGenix® rh Cytokines - Preclinical vs GMP

CellGenix® Recombinant Human Activin A is an animal-derived component-free product. It is produced in a dedicated animal-free GMP facility. Activin A is used in the cell and gene therapy space to promote differentiation of embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) into definitive endoderm, and for the maintenance and self-renewal of pluripotent stem cells (PSCs).CellGenix® Recombinant Human Activin A is produced following all applicable GMP guidelines and allows for the safe use in accordance with USP Chapter <1043>, Ph. Eur. General Chapter 5.2.12 and ISO 20399:2022.CellGenix® GMP cytokines are provided with documented evidence of purity, potency, consistency and stability. In combination with our expert regulatory and technical support this will help simplify your raw material qualification and validation efforts.Expiry: ≥ 6 months from date of shippingFor the exact expiry date and the batch specific activity, please refer to the Certificate of Analysis on the My Sartorius Portal.


App Note:

Reliable T Cell Expansion with CellGenix®️ rh IL-2

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App Note:

Performance of CellGenix® GMP TCM

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Tech Note:

ADCF and Serum-free Policy

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Tech Note:

Shipment at Ambient Temperatures

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Certificate of Analysis:

Download on the My Sartorius portal

My Sartorius

Tech Note:

Stability of GMP Cytokines after Reconstitution 

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Tech Note:

Batch-to-Batch Consistency of CellGenix® GMP Cytokines

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  • Application
    Clinical ex vivo use (small)  
  • Application Area
    • Cell & gene therapy  
    • Epithelial cell biology  
    • Stem cell biology  
  • Cell Type
    • ESC/iPSC  
    • Organoids  

Biological Information

  • Activity
    0.6 – 2.5 x 106 IU/mg  

Compliance Information

  • GMP Compliance
    This product was manufactured in accordance with applicable Good Manufacturing Practice (GMP) guidelines.  
  • Origin
    Animal-Component Free  


  • Carrier-Protein Free

Physicochemical Information

  • Endotoxin
    ≤ 0.05 EU/µg  
  • Expression System
    E. coli  
  • Formulation
    Lyophilized from a 0.2 µm-filtered solution containing 20 mM glycine, 150 mM sodium chloride and 3% mannitol, pH 9.5  

Product Information

  • Brand
  • Package Type
  • Size
    50 µg  


  • Delivery Condition
  • Purity
    ≥ 97%  


  • Molecular Weight (kDa)
    26.2 kDa