CIMac™ AAV full/empty 0.1 mL Analytical Column (1.3 µm)

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CIMac™ AAV full/empty 0.1 mL Analytical Column (1.3 µm)
 

CIMac™ AAV Analytical Columns are intended for fast and reproducible analysis and quantification in Adeno-associated virus (AAV) processes.

With a resolution high enough to resolve empty and full virus capsids and high volumetric flow ratesm they provide information about the product quantity and purity within minutes.

Item No.: 
110.8503-1.3
Piece
1

*Custom/bulk order quotes are provided within 72 hours of request.

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The CIMac™ AAV full/empty 0.1 mL Analytical Columns are designed for fast and reproducible HPLC monitoring and quantitation of AAV samples. The high resolving capacity allows separation of empty viral capsids, aggregated and damaged particles from genome containing virus vectors. CIMac™ AAV full/empty-01 Analytical Column works with a full range of AAV serotypes and samples ranging from crude harvest all the way to final formulation, therefore doubling as an efficient PAT tool.

AAV full/empty features:

  • Strong anion exchanger
  • Enables fast and reproducible analysis and quantification in Adeno-associated virus (AAV)
  • Enables separation of empty and full virus capsids

Applications

  • Application
    Analytical Columns  

Connections (Physical)

  • Connectors
    10-32 UNF coned port, 0.0625" OD tubing connection  

Dimensions

  • Channel Size
    1.3 µm  
  • Diameter
    5.2 mm  
  • Length
    4.95 mm  

Features

  • Reusable
    Yes  

General Specifications

  • Flow Rate
    0.2 – 3 mL/min | 1 – 15 cm/min | 2 – 30 CV/min  

Materials of Construction

  • Materials of Construction
    Poly(glycidyl methacrylate -co- ethylene dimethacrylate)  

Operating Conditions

  • Maximum Operating Pressure
    15 MPa | 150 bar | 2175 psi  
  • Recommended Operating Temperature
    4 °C (39 °F) to 40 °C (104 °F)  
  • pH Stability
    Working range 2–13, cleaning in place 1–14  

Physicochemical Information

  • Bed Volume
    0.1 mL  
  • Ligand
    QA modified for AAV (strong anion exchanger, quaternary amine)  

Product Information

  • Brand
    CIMac™