CIMmultus® CDI 1 mL Monolithic Column (6 μm)

CIMmultus® is a unique and industry-proven line of pre-packed chromatographic monolithic columns featuring large flow-through channels, which make them ideal for purifying large biomolecules such as viruses (AAV, adenovirus, lentivirus, influenza, bacteriophages), nucleic acids (mRNA, pDNA), virus-like particles and exosomes.

Without the need for column packing, CIMmultus® columns are ready for use out of the box.

Available in:

  • Varied monolith volumes
  • Wide range of CIM® chemistries
  • Differing channel sizes

Item No.: 
311.8000-6

*Custom/bulk order quotes are provided within 72 hours of request.

CIMmultus® Monoliths are reusable chromatography devices for scalable high-resolution purification of complex biological samples. Inside the custom-designed housing is a single-piece stationary phase with homogeneous channel size and surface chemistry. This stationary phase is designed to simplify method transfer from development into production.

Features

  • Available with a wide range of chemistries
  • Various channel size options
  • Scalable from 1 mL to 40 L
  • Single batch use or multiuse
  • cGMP compliant

Benefits

  • Very fast processes by convective mass transport – resolution independent of flow
  • Ready to use columns
  • High-capacity for large molecules due to fully accessible void volume in the channels
  • Laminar flow minimizes shear stress resulting in high yields

Applications

  • Application
    Preparative Applications  

Connections (Physical)

  • Connectors
    10-32 UNF coned port, 0.0625" OD tubing connection  

Dimensions

  • Channel Size
    6 µm  
  • Column Tube Length
    4.2 mm  
  • Inner Diameter
    6.7 mm  
  • Outer Diameter
    18.6 mm  

Features

  • Reusable
    Yes  

General Specifications

  • Flow Rate
    0.1–16 mL/min | 4.2–625 cm/h | 0.1–16 CV/min  

Materials of Construction

  • Materials of Construction
    Poly(glycidyl methacrylate -co- ethylene dimethacrylate)  

Operating Conditions

  • Maximum Operating Pressure
    1.3 MPa | 13 bar | 185 psi  
  • Recommended Operating Temperature
    4 °C (39 °F) to 35 °C (95 °F)  
  • pH Stability
    Working range 4–11  

Physicochemical Information

  • Bed Volume
    1 mL  
  • Ligand
    CDI (activated; carboxy imidazole)  

Product Information

  • Brand
    CIMmultus®  
  • Package Type
    Individually Packed