Heparin HyperD® M - 1 L

Heparin HyperD® M resin is suited for the preparative-scale purification of heparin binding proteins like coagulation factors, growth hormones, lipoproteins, and DNA/RNA processing enzymes.

Item No.: 

*Custom/bulk order quotes are provided within 72 hours of request.

Heparin HyperD® M “gel-in-a-shell” resin is comprised of a porous rigid mineral bead containing hydrogel filled pores. The heparin ligand is bound to the hydrogel.

Features and Benefits

- High dynamic binding capacity at high linear flow rate
- Rigid, non-compressible resin
- Purification of various proteins from laboratory to production scale
- Minimal ligand leakage


- Reference method for large-scale purification of antithrombin III (ATIII)
- Purification of coagulation factors such as Factor IX, Factor VII, Factor XI, Factor XII and XIIa
- Lipoprotein(LDL, VLDL, VLDL apoprotein, HDL) and lipoprotein lipase purification
- Growth hormone and growth factor (FGF, ECGF) purification
- DNA- and RNA-related enzymes
- Purification of various other enzymes (collagenase, α-L-iduronidase, hyaluronidase and lysozyme), fibronectin, fibronectin fragments and hormones receptors


  • Application
    Preparative protein purification  

Compliance Information

  • Quality Standards
    • CoA  
    • RSF  


  • Bead Size
    80 µm  

General Specifications

  • Flow Rate
    100-600 cm/h  
  • Resin Format
    Bulk resin  

Materials of Construction

  • Base Matrix
    Mineral beads  

Operating Conditions

  • Operating Pressure
    < 3 barg (44psi)  
  • pH Stability
    3 to 13 (working pH)  

Physicochemical Information

  • Ligand
    Porcine heparin  
  • Reference Protein
  • Typical Dynamic Binding Capacity 10% per mL
    25UI/mL ATIII  

Product Information

  • Brand
    Heparin HyperD® M  
  • Pack Size
  • Pack Volume
    1 L  
  • Resin Delivery Condition
    1M NaCl with 20% EtOH  
  • Resin Type
    Affinity resin  
  • What you receive
    1 bottle resin, instructions  

Storage Conditions

  • Storage Conditions
    20% EtOH/1 M NaCl