HyperCel STAR AX PRC Column - 1 mL

HyperCel Star AX is a salt-tolerant anion exchanger with a primary amine as functional group. It can easily be integrated into a purification workflow without feed stream manipulation.

Bed Volume
Item No.: 
PRCSTARAX1ML

*Custom/bulk order quotes are provided within 72 hours of request.

HyperCel STAR AX is an industry-scalable anion exchange chromatography resin designed for high productivity protein capture at moderate or higher salt conductivity (2 to 15 mS/cm), typical of undiluted biological feedstocks (e.g. mammalian cell culture supernatants, E. coli feedstock, plasma, etc.).

Features and Benefits

- High dynamic binding capacity (DBC) at short residence time (2 minutes or lower)
- Direct capture of protein from undiluted feedstock at moderate or high conductivity
- Excellent flow rate properties for fast feedstock processing
- Distinctive selectivity, consistent in a broad conductivity range (2 – 15 mS/cm)
- Enhanced process economics
- Manufactured at large scale and to meet the demands of commercial users and regulatory authorities

Applications

- Direct capture of recombinant proteins, mono- and poly-clonal antibodies, plasma derivatives
- Direct Capture of Albumin from Undiluted Plasma
- Early Removal of CHOPs before Protein A Capture of a Monoclonal Antibody (MAb)

Applications

  • Application
    Resin screening and process optimization

Compliance Information

  • Quality Standards
    CoA

Dimensions

  • Bead Size
    60 - 90 µm
  • Bed Height
    50 mm
  • Dimensions
    5 x 50 mm

General Specifications

  • Flow Rate
    100-300cm/h
  • Resin Format
    Pre-packed column

Materials of Construction

  • Base Matrix
    Rigid cellulose beads
  • Materials of Construction
    Polypropylene

Operating Conditions

  • Operating Pressure
    < 3 barg (44psi)
  • pH Stability
    1 to 14 (short term), 2 to 12 (long term)

Physicochemical Information

  • Bed Volume
    1 mL
  • Ligand
    Primary amine (PA)
  • Reference Protein
    Bovine serum albumin (BSA)
  • Typical Dynamic Binding Capacity 10% per mL
    > 100 mg/mL BSA at pH 7.5 to 8.0 and conductivity to 15 mS/cm

Product Information

  • Brand
    HyperCel STAR AX
  • Pack Size
    1 column per pack
  • Pack Volume
    1 mL
  • What you receive
    1 column, instructions

Storage Conditions

  • Storage Conditions
    20% EtOH/1 M NaCl