Octet® R8, 8-Channel Protein Analysis System

Top Features of Octet® R8

  • Unmatched Flexibility and Versatility: Eight parallel and independent channels that offer speed, sensitivity, and flexibility
  • Unattended Run Time: An optional cover reduces sample loss suitable for longer un-attended runtimes
  • Upgrade to GxP: Octet® R8 GxP package ensures regulatory compliance with CFR21 Part 11 software, IQOQ/PQ kits, protocols, and services. Non-GxP systems can be upgraded to GxP systems for regulatory compliance.

Popular Applications for Octet® R8

  • Binding Kinetics and Affinity
  • Concentration analysis
  • Potency analysis Epitope binning

Item No.: 
OCTET-R8
Availability: 

*Custom/bulk order quotes are provided within 24 hours of request.

The Octet® R8 system is a versatile tool that can be used for a wide range of analyses, such as kinetic analysis, titer of IgG and other proteins, reagent qualification, immunoassay development, bioprocess development, quality control, crude antibody screening, epitope binning/mapping, ligand binding assays, small molecule analysis, elucidating cell signaling mechanisms, and infectious disease monitoring. You can perform analysis using a single channel or up to eight channels, giving you flexibility in sample throughput.

  • High Throughput and Flexibility: The Octet® R8 system has eight independent channels, allowing for maximum speed, sensitivity, and flexibility. It can perform analyses of up to 96 samples in as little as 30 minutes to 2.5 hours, catering to different sample throughput needs. It's suitable for a range of analyses, including kinetic analysis, titer determination, immunoassay development, and more.
  • Advanced Kinetic Screening and Versatility: Produces High-quality kinetic screening and affinity characterization by monitoring binding events in real-time to calculate on-rates (ka), off-rates (kd), and affinity constants (KD). The Octet® R8 is versatile and can detect a wide range of biomolecules, including small molecules, proteins, viruses, and nanoparticles, making it suitable for various research and development applications.
  • GxP Compliance and Unattended Run Capability: Octet® R8 is designed for GxP-regulated environments. It comes with an optional GxP package that includes 21 CFR Part 11 software and IQOQ/PQ kits for regulatory compliance. It has an optional evaporation cover that minimizes sample volume losses, allowing for up to 12 hours of unattended run time and post-analysis sample recovery.

Features

  • Operation
    Automated
  • Plate Compatibility
    96 Well
  • Sample Plate Capacity
    1

General Specifications

  • Affinity Range
    1 mM to 10 pM
  • Analysis time per 96 samples (Concentration)
    30 min
  • Analysis time per 96 samples (Kinetics)
    2.8 hr
  • Analyte MW Range
    > 150 Da
  • Association rate
    10¹ to 10⁷ M⁻¹ s⁻¹
  • Channels
    8
  • Crude sample compatibility
    Yes
  • Dissociation rate
    10⁻⁶ to 0.1 s⁻¹
  • External Automation
    No
  • Orbital Flow Capacity
    Static or 1000 – 2,600 RPM
  • Temperature Range
    15-40 C

Operating Conditions

  • Minimum Operating Volume
    200 µL

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