Sartopure® PP3 Prefilter for Particle Retention
Discover the Sartopure® PP3 filter line, the high-performance solution for crucial particle reduction and protection of valuable downstream filtration steps in biopharmaceutical manufacturing. This scalable platform employs fleece filter technology for consistent results across process development and production scales.
The Sartopure® PP3 system utilizes multiple layers of polypropylene fleece with differing retention ratings, enabling retention of a large amount of particles through fractionized fleece filtration and achieving high dirt-holding capacity.
Key Features and Benefits
- Optimize Process Economy: The demonstrated retention capability and high throughput performance enable the downsizing of required filtration areas, potentially reducing overall filter consumption and costs.
- Ensure Process Reliability: The unique retention performance of the fleece material provides exceptional robustness, retaining particles with high efficiency even under varying process conditions.
- Maximize Product Yield: The all-polypropylene design ensures low unspecific binding, enhancing the recovery of valuable therapeutic products.
- Broad Compatibility: Filter elements consist entirely of polypropylene, offering broad chemical compatibility with a wide range of solvents, acids, and bases.
Format Flexibility and Scale-Up
The Sartopure® PP3 filter line is a comprehensive platform available in multiple formats to facilitate seamless transitions from initial screening to full production.
- Scalable Formats: Available as Cartridges, T-Style Maxicaps®, In-line Maxicaps®, Midicaps®, Mini Cartridges, Capsules, and Sartoscale units.
- Retention Ratings: A comprehensive range of ratings is available from 0.45 µm up to 50 µm, addressing diverse prefiltration requirements.
Applications
Sartopure® PP3 prefilters are ideally suited for numerous applications requiring efficient clarification, particle removal and protection of subsequent sterile filtration steps:
- Protection of downstream membrane filtration equipment.
- Clarification steps in vaccine production.
- Processing of viral vectors, specifically Lentivirus.
- Filtration of large volume parenterals and ophthalmic solutions.
- Processing of antibiotics and solvents.
- Processing of plasmid DNA (pDNA).
