Vivaflow® 50, 100,000 MWCO PES, 2pc

100 ml - 3 l

  • Plug and play laboratory cross flow cassette
  • Modular - scalable to 6 units
  • Disposable
  • Optimal for aqueous sample concentration e.g. proteins and nanoparticles
  • High flow rate and recovery

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*Custom/bulk order quotes are provided within 24 hours of request.

Vivaflow® 50 is a disposable and ready-to-use crossflow cassette for filtration and concentration of samples from 100 ml to 3 l. The membrane surface per device is 50 cm2. One pack contains two devices and comes with all necessary accessories for running two devices with a laboratory pump and a size 16 pump head. For speeding up the concentration and increasing the volume throughput, six cassettes can be connected.

Optimally suited for applications like cell culture supernatant concentration, virus concentration and water concentration e.g. in fish breeding facilities, this economical product offers a standard of ease of use, reliability and flexibility unrivalled by any laboratory filtration system in the market. The thin-channel, flip-flow recirculation path of the modules provides high crossflow velocities with minimum pump speed requirements. A single 50 cm2 module typically reduces 500 ml to 15 ml in less than 50 min. Nearly total recovery of the concentrate is achieved with a single rinse. Up to six of the unique interlocking modules can be connected for easy scale up resulting in a capacity of several liters. Vivaflow® 50 is intended for single use. All accessories for sample concentration, except a peristaltic pump with a pump head for size 16 tubing, are included in the package. A 500 ml sealed diafiltration reservoir can be added to the system for rapid and convenient buffer exchange.

Equipment required

The standard Vivaflow® 50 package comes with two cassettes, tubing, flow restrictor, one series interconnector and high pressure pump tubing. All you need is a peristaltic pump with a pump head capable of handling 6.4 mm OD tubing (size 16).

Running more than two Vivaflow® 50 devices in parallel and series

For speeding up the concentration, as many as six Vivaflow® 50 cassettes can easily be connected using 2 T-connectors for connecting 2 Vivaflow® cassettes at the inlet and at the outlet and series interconnectors for connecting the devices inbetween. A pressure indicator needs to be built in the inlet for optimal control.

  • High flow rate and recovery
  • Clear housing for process monitoring
  • Ready to use single cassettes
  • Easy set up of multiple cassettes
  • Economical and disposable product
  • Unique in its performance

A single 50cm2 module will typically reduce 500 ml to less than 15 ml in under 50 minutes. Less than 10 ml minimum system recirculation for highest concentrations. Less than 1.5 ml non recoverable hold up volume. Near total recoveries achievable with a single 10 ml rinse.



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  • Application
    Protein Concentration  
  • Application Area
    Buffer exchange  
  • Intended Use
    Research Use Only (RUO)  
  • Market

Compliance Information

  • Animal Components
  • CSA Compliant
  • Certification
  • Electrical / Battery item

Connections (Physical)

  • Fittings
    Nylon (NY)  


  • Channel Height
    0.3 mm  
  • Channel Width
    15 mm  
  • Membrane Area
    50 cm²  
  • Overall Height
    84 mm  
  • Overall Length
    107 mm  

General Specifications

  • Pump Flow
    200 – 400 mL/min  
  • Tubing
    PVC (medical grade)  

Materials of Construction

  • Flow Channel
    TPX (PMP)  
  • Flow Restrictor
    Polypropylene (PP)  
  • Housing Material
    Polycarbonate (PC)  
  • Material o-ring | seal
    Silicone (SI)  
  • Membrane Material
    Polyethersulfone (PES)  
  • Membrane Support
    TPX (PMP)  
  • Pressure Indicator
    Polypropylene (PP), Stainless Steel (SS), Polyoxymethylene (POM), Silicone (SIL), Polyamide (PA)  

Operating Conditions

  • Maximum Allowable Working Temperature
    60 °C (140 °F)  
  • Maximum Operating Pressure
    3 bar (44 psi)  

Physicochemical Information

  • MWCO
    100 kDa  
  • Non-recoverable Hold-up
    < 0.5 mL  
  • Pore Size

Product Information

  • Brand
  • Device Type
    TFF – (Crossflow)  
  • Pack Size
  • Sample Type
    • Protein  
    • Peptide  
    • Nanoparticles  
    • Virus  
    • Endotoxin  


  • Dead Stop Volume
  • Hold-up Volume
    1.5 mL  
  • Minimum Recirculation Volume
    10 mL  
  • Volume Range
    100 – 3,000 mL  
  • Replacement Tubing Set for Vivaflow®


    Tubing Set for Vivaflow® 50

    Comprises: 2 x 1 m size 16 PVC tubing with inlet fittings, 2 x 50 cm size 16 PVC tubing with 0.6 mm flow restrictors, 1 x series interconnector

  • Flow Restrictors, 0.6 mm, 6pc


    Flow restrictor 0.6 mm (6 pieces)

    Flow restrictors 6 x 0.6 pink to be used with the Vivaflow® systems

  • Pressure Indicator, 1-3 bar


    Pressure Indicator (1-3 bar)

    Pressure indicator (1-3 bar) for Vivaflow® units

  • Cassette Stand for Vivaflow® 50


    Plate used for setting up Vivaflow® 50 units

    Vivaflow® 50 stand

  • Peristaltic Pump Drive, 115v


    Pumps used for filtration. Choose from a broad range of universal pumps and manual pumps over laboratory vacuum pumps to peristaltic pumps.

  • Series Interconnectors, Size 16, 6pc


    Series Interconnectors (6 pieces)

    Series interconnectors for running up to six Vivaflow® 50 units in parallel

  • Peristaltic Load Pump Head, Size 16


    Masterflex Easy Load Pump Head - Size 16

  • T-Connectors, Size 16, 2pc


    T Connectors for Vivaflow® 50 (2 pieces)

    T connectors for running 2 stacks of Vivaflow® 50

  • Sample and Diafiltration Reservoir, 500 mL


    500 ml sample|diafiltration reservoir to be used with Vivaflow® systems. Allows the convenient application of samples and the continuous replacement of buffer.

  • Luer Fittings, Female to Size 16 Hose Barb, 10pc


    Female Luer fittings Size 16 (10 pieces) to be used with the Vivaflow® systems