Study factors for manufacturability Collect important information about the behaviour of the molecules in downstream processing already in an early stage Automated, parallel trials Up to 16 channels can be managed by one control station Lowest process volumes Small scale screening with 10 cm² membrane area | 5 mL recirculation volume Flexibility of two different process scales Mid-scale screening is also possible with Sartocon® Slice 50 which has 50 cm² membrane area
The Sartorius Sartofluor® Air Filter ensures sterile air with a single-layer PTFE membrane, offering high flow rates and validated sterility across various conditions, with a cost-effective performance for air/gas and solvent filtration.
Sartobind® Q strong ion exchangers are perfect tools for the polishing of monoclonal antibodies for the removal of viruses, DNA, host cell proteins, leached Protein A, and endotoxins. As size exclusion effects are neglectible, they are suited for purification of viruses such as adeno or lentiviruses displaying one order of magnitude higher dynamic binding capacity.
The Hollow Fiber TFF Modules | Single-use Line offer a true single-use tangential flow filtration solution. A broad variety of different pore sizes and molecular weight cut-offs (MWCO) ensure a suitable solution for a wide range of processes. The scalability ranging from Lab- over Pilot- up to Process-scale increases flexibility in each stage of production. Hollow Fiber TFF Modules | Single-use are delivered gamma irradiated, fully integrity tested and therefore ready-to-use. Since, no cleaning is required you can save valuable time.
The Steamer Line Hollow Fiber TFF Modules are designed for perfusion and aseptic applications. They are delivered gamma irradiated and ready to use and can be autoclaved.
Reuse Line modules are designed for multiple use cycles. The Reuse module can be easily cleaned after each use. The choice of cleaning solution, cleaning time and frequency will depend on the specific process stream, fouling tendency and operating conditions.
HA Ultrogel® is a composite material of cross-linked agarose and microcrystalline hydroxyapatite enclosed in the agarose matrix. The material shows mixed mode functionality based on cation exchange and metal affinity in the hydroxyapatite structure. A wide variety of applications include separation of proteins, peptides and nucleic acids, from laboratory to production scale.
Sartobind STIC® PA (primary amine) anion exchange membrane overcomes reduced binding capacity for host cell protein removal and can be used in high-salt conditions.
The PES based virus filter for robust and efficient removal of small non-enveloped and large enveloped viruses in biopharmaceutical applications. Virosart® CPV is the optimal virus filter for monoclonal antibodies or small recombinant proteins.
MEP HyperCel provides a unique separation mechanism and selectivity for protein separations, with ligand-based immunoglobulin selectivity optimal for monoclonal antibody capture and intermediate purification. The MEP ligand facilitates the binding of immunoglobulins as well as other target proteins at neutral pH under moderate salt concentrations.
Sartoclean® family is a cellulose acetate (CA) membrane based prefilter. These filters are optimized for the protection of downstream equipment and Sartobran® cellulose acetate final filters.
Maximize your virus filter performance with adsorptive pre-filtration. Virosart® Max is a specifically optimized virus pre-filter significantly increasing downstream virus filter performance.
The Ambr® Crossflow DF1, DF2 and Feed Bottle Kit contains:
2 x 500ml glass bottles with caps, breathers and tubing assemblies for one channel 1 x 100ml glass bottle with caps, breathers and tubing assemblies for one channel
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Item no.SECURA6102-1NUSBrandSecura®AdjustmentInternal automatic (isoCAL)Anti-Theft Locking DeviceKensington Lock, lockdown capability for cable or chainApplicationResearch