The family of Sartorius TFF filter holders features the latest advances in TFF design for full flexibility. This unique design within the Sartoflow® filter holder family provides you with a reproducible performance from 30 - 2.500 L process volumes.
Sartorius Stedim removable housing heaters are used in onjunction with sterile vent and process filter housings and are ideally suited for processes such as:
Bioprocessing and Pharmaceutical Process Fluids Fermentation Product Recovery Water for Injection Filtration and Purification Processes Skidded Systems Tanks and Vessels
The Vero cell line is used for various purposes, most importantly for the production of cell culture-based viral vaccines. Reasons for the extensive use of the Vero cell line are the consistent high viral yields and susceptibility to infect a mutiple range of viruses, as well as relatively easy adaptation for growth in bioreactors on microcarriers, thus allowing up-scaling without loss of cell productivity.
Microcarriers are a support matrix allowing for expansion of adherent cells in the suspension culture. They are offered in both non-sterile autoclavable and sterile gamma-irradiated ready-to-use format to serve both research and manufacturing need. All microcarrier types are manufactured using solid modified polystyrene cores and surfaces are modified with proprietary chemistries to enhance cell attachment and growth performance across multiple adherent cell types. SoloHill® microcarrier types do not require lengthy pre-conditioning steps prior to their use in the cell culture processes and their basic properties facilitate simple cell detachment.
Sartocell® F&B filter modules are stackable, cellulose based depth filtration modules for use in stainless steel housings. The robust modules combine the advantages of a closed filtration system with an excellent stability and long service life of the modules.
The Sartopure® filter family is optimized for the clarification and retention by utilizing multiple layers of progressively finer pleated polypropylene or adsorptive glass fleece material. The turbidity reduction results in optimal protection of all downstream material like chromatographic columns or membrane filters.
DEAE Ceramic HyperD® F is a weak anion exchanger for biomolecule purification. Changes in conductivity and pH can optimize purification steps by utilizing the charge change on protein and ligand.
Our high performing HEK media are designed to best fit with the high variability of HEK293 cell lines, the versatility of AAV and complexity of viral vector processes from early clinical phases to large commercial scale. Human embryonic kidney (HEK 293) cells and human cell lines are commonly used for Gene Therapy applications (AdenoAssociated Virus) , Gene Modified Cell therapy (Lentivirus), Viral vector Vaccines( Adenovirus) and Proteins production.
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