Sartopore® 2 XLM

Sartopore® 2 XLM Filters: Sterilizing-Grade & Mycoplasma Retentive Solutions

Introducing Sartopore® 2 XLM filters, the ultimate solution for ensuring the highest level of sterility and Mycoplasma retention in cell culture media. Designed with advanced filtration technology, these filters offer unparalleled protection against Mycoplasma contamination, making them indispensable in biotech manufacturing processes.

Key Features

• Advanced Filtration Membranes: Equipped with a 0.1 µm Mycoplasma retentive filter membrane, Sartopore® 2 XLM filters effectively block Mycoplasma, which can penetrate standard 0.2 µm filters. The 0.2 µm prefilter layer safeguards the final membrane, enhancing the overall filtration process and extending filter life.
• The XL family: The XL in its name indicates an increased effective filtration area. Thanks to a different pleating technology, these filters offer a 30-40% larger EFA compared to conventional Sartopore® 2 filters, depending on the format. This enhancement results in greater total throughput per filter element, reducing filter consumption and allowing for smaller filter elements, thereby minimizing both footprint and waste.
• Scalability: Available in a wide range of sizes and formats, ensuring seamless scale-up from research and development to full-scale production in the range from 4.5 cm² up to 2.4 m² per filter element, providing.
• Fully Validated: Validated as sterilizing-grade filters, ensuring reliable bacterial retention and proven to retain Acholeplasma laidlawii and Leptospira licerasiae, meeting stringent ASTM F-838 guidelines.
  

Applications

Typical applications include sterilizing-grade filtration and Mycoplasma removal from

• Plant peptone or yeast supplemented cell culture media
• Chemically defined cell culture media
• Cell culture media components such as serum (e. g. Fetal Calf Serum)
• All other cell culture media used in biotech manufacturing

Benefits

• Enhanced Sterility Assurance: Minimizes the risk of Mycoplasma contamination, which is crucial for maintaining the integrity of cell culture processes. Sartopore® 2 XLM filters are fully validated for sterilizing-grade applications, offering peace of mind in critical biotech operations.
• Cost-Effective Filtration: High filtration capacity leads to reduced filter consumption, lowering operational costs. The optimized design minimizes downtime and maximizes productivity.
• Regulatory Compliance: Meets or exceeds requirements for Water for Injection (WFI) quality and non-pyrogenic standards. The filter complie with USP Bacterial Endotoxins and USP Plastic Class VI Test, ensuring safety and reliability.
• PFAS restrictions: Made without intentionally using PFAS compounds to ensure you are prepared for potential future restrictions.
  

Sartopore® 2 XLM filters are the epitome of advanced filtration technology, offering unmatched performance in Mycoplasma retention and sterilizing-grade applications. With their robust design, scalability, and comprehensive validation, these filters are the ideal choice for biotech manufacturers seeking reliable and cost-effective filtration solutions.