Resolute® BioSMB Platform

Single-Use Multi-Column Chromatography

Resolute® BioSMB PD and BioSMB 80|350 chromatography systems are designed to purify biologics from process development to commercial manufacturing scale.

  • Easily scalable single-use platform
  • Harmonized good manufacturing practice (GMP)-ready software across the entire Resolute® BioSMB platform
  • Up to 80% reduction in resin volumes and costs

Choose your product

Products (7)

  • Resolute® BioSMB PD
    Item no.
    BIOSMB-PD-LD100B
    Application Area
    Process development, Clinical manufacturing
    Line Voltage
    100–240 VAC, 50–60Hz
    Power Requirements
    380 W
    Volume
    1-100 mL/min
  • Resolute® BioSMB Additional 80 Pump Module
    Item no.
    BIOSMB-PRO-080-PUM
    Application Area
    Clinical manufacturing, Commercial manufacturing
    Volume
    5 – 80 L/h
  • Resolute® BioSMB 80 for UL
    Item no.
    BIOSMB-PRO-080-UL
    Application Area
    Clinical manufacturing, Commercial manufacturing
    Line Voltage
    208 VAC 50 | 60 Hz
    Power Requirements
    32A – 15kW
    Volume
    5 – 80 L/h
  • Resolute® BioSMB 80 for CE
    Item no.
    BIOSMB-PRO-080-CE
    Application Area
    Clinical manufacturing, Commercial manufacturing
    Line Voltage
    400 VAC 50 | 60 Hz
    Power Requirements
    32A – 15kW
    Volume
    5 – 80 L/h
  • Resolute® BioSMB Additional 350 Pump Module
    Item no.
    BIOSMB-PRO-350-PUM
    Application Area
    Clinical manufacturing, Commercial manufacturing
    Volume
    30 – 350 L/h
  • Resolute® BioSMB 350 for CE
    Item no.
    BIOSMB-PRO-350-CE
    Application Area
    Clinical manufacturing, Commercial manufacturing
    Line Voltage
    400 VAC 50 | 60 Hz
    Power Requirements
    32A – 15kW
    Volume
    30 – 350 L/h
  • Resolute® BioSMB 350 for UL
    Item no.
    BIOSMB-PRO-350-UL
    Application Area
    Clinical manufacturing, Commercial manufacturing
    Line Voltage
    208 VAC 50 | 60 Hz
    Power Requirements
    32A – 15kW
    Volume
    30 – 350 L/h
  • The Resolute® BioSMB PD and BioSMB 80|350 systems are multi-column chromatography systems designed to increase the efficiency and productivity of fed-batch, intensified fed-batch, and perfusion processes during chromatography unit operations. Multi-column chromatography (MCC) using Resolute® BioSMB reduces resin usage by up to 80% without impacting critical chromatography processes. This presents a significant saving on operational expenditure, particularly when considering affinity capture steps.

    Applications

    • Application
      • mAB Production
      • Antibody Purification
      • Polishing
      • Capture
      • Affinity
      • Large Molecules
    • Application Area
      • Process development
      • Clinical manufacturing
      • Commercial manufacturing

    Product Information

    • Brand
      Resolute®